Black eschar on the palate

Introduction Black ankles in the ankle are common in pulmonary mucormycosis. Pulmonary mucormycosis is a pulmonary infectious disease caused by Mucormycosis. Although rare, it develops rapidly and has a high mortality rate. Clinically, mucor and rhizopus are more common. The former mainly invades the lungs, and the latter mostly affects the sinuses, eyes, brain and digestive tract, and can spread to the whole body. Pulmonary mucormycosis can be a primary infection or secondary to sinus lesions or mucormycosis. The disease begins with acute bronchitis symptoms, which cause lung consolidation and lung abscess when the lungs are involved, accompanied by signs of thrombosis and infarction.

Cause

Commonly due to fungal infections, fungi mainly belong to the genus Zymenia, Mucor, Mucor, Mucor, and other families in the genus Mucor, such as the genus Mortier, the genus Caused by the science of Keke mold, bottle mold. Among them, Rhizopus, Mucor, and Absidia are the most common 3 types of fungi causing pulmonary mucormycosis, and the most common types of fungi are caused by Rhizopus. Rhizopus and Rhizopus oryzae.

an examination

Related inspection

Molybdenum target X-ray examination oral endoscope

1. The histopathology of pulmonary mucormymosis is non-specific, mainly based on the discovery of coarse hyphae without separation or separation in the tissue sections, with little or no cellular response. Its characteristic change hyphae is easy to invade the large and small arterial wall, leading to infarction, causing necrosis of adjacent tissues.

2. Laboratory examination

(1) Direct microscopic examination: specimens from the upper turbinate scrapings, sinus aspirate, sputum and biopsy specimens, direct microscopic examination with 20% potassium hydroxide, showing typical thick-walled refraction hyphae The diameter is 6-15 m, and expanded cells and curved hyphae can also be seen. The cystic stem is directly grown by hyphae, and the hyphae can be branched at right angles.

(2) Culture: The clinical specimens were inoculated into the maltose medium without the cycloheximide, the potato medium and the common Sabour medium, and cultured at 37 ° C or 25 ° C, the growth was faster, and the surface of the colony was cotton-like. , white, gradient to taupe or other colors. Pulmonary mucormycosis is dangerous, and mucormycosis often pollutes the environment and the environment, so direct microscopic examination is often more meaningful than culture.

3. Other auxiliary examinations: X-ray films show non-specific pneumonia and pulmonary infarction.

Differential diagnosis

Often identified with oral ulcers. Oral ulcers, also known as "mouth sores", are superficial ulcers that occur on the oral mucosa. They can vary in size from rice to soybeans, round or oval, and the ulcer surface is concave and concave around the mouth. Irritating foods cause pain and usually heal itself in one to two weeks. Oral ulcers occur periodically and repeatedly, medically known as "recurrent oral ulcers." It can occur several times a year, or it can occur several times a month, and even new and old lesions appear alternately.

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