Bacterial colitis
Introduction
Introduction to bacterial colitis The pathogenesis of bacterial enteritis is complicated, and the pathogenic bacteria adhere to the epithelial cells of the intestinal mucosa by the bacteria, so that the bacteria can grow and reproduce in the intestinal wall, which becomes a prerequisite for disease. The pathogen of bacterial enteritis can be divided into two major categories of enterotoxin and invasiveness. Enteritis caused by different pathogens has different pathogenesis and clinical manifestations. basic knowledge Sickness ratio: 0.05% Susceptible people: no specific population Mode of infection: non-infectious Complications: dehydration, electrolyte imbalance
Cause
Cause of bacterial colitis
The cause of bacterial enteritis:
The pathogen of bacterial enteritis can be divided into two major categories of enterotoxin and invasiveness. Enteritis caused by different pathogens has different pathogenesis and clinical manifestations.
Enterotoxin-induced bacterial enteritis:
Such as cholera, the pathogenesis is the adhesion of pathogenic bacteria without invading the intestinal mucosa, secreting enterotoxin during bacterial growth and reproduction, and binding to the epithelial membrane receptor of the small intestinal mucosa, activating adenylate cyclase on the cell membrane, Under the catalysis of the enzyme, intracellular adenosine triphosphate (ATP) is converted into cyclic adenosine monophosphate (cAMP). When the level of intracellular cAMP is elevated, a large amount of water and electrolyte are secreted by the small intestinal mucosa through a series of enzymatic reactions, which are retained in the intestinal lumen to cause watery diarrhea, which is called "secretory diarrhea." In addition to hypersecretion of small intestinal mucosal epithelial cells, the pathological changes in the intestinal tract are often absent or very light.
Invasive bacterial enteritis:
Such as bacterial dysentery, pathogenic bacteria adhere to and invade the intestinal mucosa and submucosa, causing significant inflammation. Different pathogens invade the intestines, some invade the small intestine, some invade the colon, and some cause inflammation of the small intestine and colon.
Prevention
Bacterial colitis prevention
1. Do a good job in environmental sanitation, strengthen toilet and manure management, eliminate flies and breeding grounds, and mobilize people to eliminate flies.
2. Strengthen food hygiene and water source management, especially for individuals and food vendors to conduct health supervision and inspection.
3. The cooks and caregivers of the collective units and child care institutions should regularly check the stool and do bacterial culture.
4. Strengthen health education. Everyone should wash their hands before and after meals, do not lead to water, do not eat spoilage and rotten food, and do not eat food that has been contaminated by flies.
5, do not overeating, so as not to reduce the resistance of the gastrointestinal tract.
Complication
Bacterial colitis complications Complications dehydration electrolyte disorder
Dehydration, electrolyte imbalance and acidosis are prone to occur, and symptoms of systemic poisoning are mild. Dehydration and acidosis are the main fatal causes of acute diarrhea. The carbon dioxide produced by metabolism in the body is usually excreted through the breath. The rest of the waste needs to be transported through the kidneys and excreted from the urine. When dehydration, the amount of urine is reduced due to the loss of water in the body. In severe cases, there is no urine. This will reduce the discharge of waste from metabolism in the body and accumulate in the body, causing symptoms of poisoning in the body. In addition to respiratory changes, the clinical manifestations can be There is fatigue and nervousness and nervous system symptoms.
Symptom
Bacterial symptoms of colonic inflammation Common symptoms, diarrhea, mucus, feces, pus, blood, sputum, re-discharge, not enough, unexplained, fever
Symptoms of bacterial enteritis:
Fever, diarrhea, mucus or pus in the stool, odor in the stool, and some have a sense of urgency, even if there is still a feeling of unfinished afterwards.
Enterotoxin-induced bacterial enteritis:
The pathogen mainly infects the small intestine, so the basic clinical manifestations are more frequent diarrhea, a large amount of watery stool, no pus and blood, generally no abdominal pain, no urgency, often accompanied by vomiting, prone to dehydration, electrolyte imbalance and acidosis, systemic poisoning The symptoms are mild.
Invasive bacterial enteritis:
The basic clinical manifestations of this type of enteritis are: systemic toxemia is obvious, there is high fever, septic shock can occur in critically ill patients. Large can be mucus pus and blood, it will be less, it will be more. Abdominal pain is obvious, with paroxysmal colic.
Examine
Examination of bacterial colitis
Bacterial enteritis needs to be checked:
1. Electrolyte inspection;
2, stool examination;
3, vomit check;
4. Sigmoidoscopy.
Diagnosis
Diagnosis and identification of bacterial colitis
Diagnosis of bacterial enteritis:
Generally judged according to the history of epidemiology and clinical manifestations. Further diagnosis depends on laboratory tests. Bacterial enteritis can be used for vomiting and stool culture, and pathogens can be diagnosed. Some pathogens such as Salmonella infection can be used for blood culture.
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