Neonatal invasive Escherichia coli enteritis

Introduction to neonatal invasive E. coli enteritis Enteroinvasive Escherichia coli mainly causes disease in large children and adults. Newborns have a poor susceptibility to this bacterium. There have been no reports of outbreaks among small babies. There have been cases of prevalence in schools, military units, associations and hospitals, but more are sporadic cases. basic knowledge The proportion of illness: 0.015% Susceptible people: good for newborns Mode of infection: digestive tract spread Complications: bacteremia, hemolytic uremic syndrome, arthritis

Neonatal invasive E. coli enteritis cause

Cause

Enteric infectious diseases caused by EIEC. EIEC is a group of diarrhea-causing Escherichia coli isolated from the stool of "dysentery" patients in 1967. EIEC and Shigella have similar biochemical characteristics, no power, no fermentation of lactose or slow fermentation, common antigen, all invasive pathogenic bacteria, also known as dysentery-like Escherichia coli, can invade epithelial cells, and Among them, growth and reproduction cause an inflammatory reaction. It is necessary to pay attention to the identification of the two, and the identification medium has a citrate medium and a sodium acetate medium. Common O serotypes are: O28, O29, O32, O112, O124, O136, O143, O144, O152, O164, O167 and the like. EIEC does not produce enterotoxin, which mainly invades the colon and forms intestinal wall ulcers. It is highly viral, and it can be caused by only 10 to 100 bacteria. Polluted water and food can cause outbreaks, and can also be spread by contact to form sporadic cases. Adults and children can be ill.

Pathogenesis

EIEC invades intestinal mucosal epithelial cells, which release endotoxin after the death of bacteria, destroying cells to form inflammation and ulcers, causing diarrhea. Less common in clinical practice, mainly infringing older children and adults. The clinical manifestations are similar to dysentery

Neonatal invasive E. coli enteritis prevention

1. Wash hands before and after meals to protect the food source.

2. Maintain good personal, food and environmental hygiene.

Neonatal invasive E. coli enteritis complications Complications bacteremia hemolytic uremic syndrome arthritis

Intestinal complications of invasive E. coli enteritis are rare.

1, bacteremia

Bacteremia is mainly seen in children, with malnutrition, sickle cell anemia and immunocompromised patients. There are more than 100 cases in foreign countries, and there are also a few cases reported in China. The symptoms of bacteremia are more serious, and the mortality rate is as high as 46%. Bacteremia is more common in 1-2 days after onset, antibiotic treatment is effective.

2. Hemolytic uremic syndrome

Hemolytic uremic syndrome is mainly found in Shigella serovar infections of Shigella dysenteriae. Some cases begin with a leukemia-like reaction, followed by hemolytic anemia and DIC. Some cases have acute renal failure, renal arteries have thrombosis and renal cortical necrosis, fibrin deposition in the glomeruli and arterial wall, about half of the cases are positive for sputum test, and most cases are positive for immune complexes in serum. Endotoxemia may be related to the onset, but endotoxemia caused by other bacteria does not have similar performance. The prognosis of this disease is serious.

3, arthritis

Arthritis often occurs within 2 weeks after the dysentery, which may be caused by allergic reaction, mainly involving large joints, which can cause redness and exudation of the knee and ankle joint. There is an antibody that binds Shigella in the joint fluid, and the serum anti-O" titer is normal. Treatment with hormones can be quickly relieved.

Neonatal invasive E. coli symptoms of common symptoms, high fever, abdominal pain, diarrhea, urgency, and blood in the stool

Invasive E. coli enteritis manifested as fever, abdominal pain, diarrhea, urgency, and pus and bloody stools.

Examination of neonatal invasive E. coli enteritis

At the same time, the Escherichia coli obtained from stool culture was also positive for the guinea pig cornea test.

Diagnosis and identification of neonatal invasive Escherichia coli enteritis

diagnosis

Determining the diagnosis must be positive for the EIEC serum agglutination test.

Differential diagnosis

Clinical attention is distinguished from bacillary dysentery.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.