Megagyrus

Introduction to Giant Brain Back Malformation Giant brain gyrus is an incomplete cerebral regurgitation, which is only involved in the reduction of cerebral gyrus and increased volume. The giant brain gyrus is firstly reduced by the cerebral gyrus. In severe cases, only the main cerebral gyrus can be found. The giant gyrus is often combined with no cerebral gyrus. Giant brain gyrus is caused by the development of the brain in the original stage, that is, the germ layer. Developmental disorders occurred 2 months before the embryo. Under the microscope, it was found that the four layers of the original cortex remained, the cortical structure was incomplete, and the neural cells were immature. Due to the disorder of the neuroblasts to the surrounding, ectopic nerve cells are often found in the white matter, and sometimes the group is nodular. Ectopic gray masses can be seen in the center of the semi-oval center, the white matter of the cerebellum, and the brainstem. Severe cases manifest as mental retardation, and even can not survive after birth, survivors often have mental retardation, accompanied by epilepsy, and poor prognosis. basic knowledge Sickness ratio: 0.0001% Susceptible people: infants and young children Mode of infection: non-infectious Complications: epilepsy, mental retardation, congenital malformation of the brain

Cause of giant brain gyrus

Cause

Giant brain gyrus is caused by the development of the brain in the original stage, that is, the germ layer develops disorder 2 months before the embryo. Under the microscope, it was found that the four layers of the original cortex remained, the cortical structure was incomplete, and the neural cells were immature. Due to the disorder of the neuroblasts shifting to the periphery, the ectopic nerve cells are often found in the white matter, and sometimes the group is nodular. Ectopic gray masses can be seen in the center of the semi-oval center, the white matter of the cerebellum, and the brainstem.

Giant brain back deformity prevention

Precautionary measures refer to birth defects, and prevention should be carried out from pre-pregnancy to prenatal:

Pre-marital medical examination plays an active role in preventing birth defects. The size of the effect depends on the examination items and contents, including general physical examination (such as blood pressure, electrocardiogram) and family history of the disease, personal medical history, serological examination (such as hepatitis B virus, Treponema pallidum, HIV), reproductive system tests (such as screening for cervical inflammation).

Systemic birth defect screening is required during antenatal care during pregnancy, including regular ultrasound, serological screening, and, if necessary, chromosomal examination.

Pregnant women should avoid harmful factors as much as possible, including away from smoke, alcohol, drugs, radiation, pesticides, noise, volatile harmful gases, toxic and harmful heavy metals.

The cause has not yet been fully elucidated, and genetic counseling should be done to do all the health care work during pregnancy. Once an abnormal result occurs, it is necessary to determine whether to terminate the pregnancy; the safety of the fetus in the uterus; whether there is sequelae after birth, whether it can be treated, and how the prognosis is. Take practical and feasible treatment measures.

Giant brain dysplasia Complications, epilepsy, mental retardation, congenital malformation

Often complicated by epilepsy, mental retardation, congenital malformations of the brain.

Giant brain gyrus symptoms common symptoms mental retardation brain dysfunction mental retardation

Giant brain gyrus is an incomplete cerebral regurgitation, which is only involved in the reduction of cerebral gyrus and increased volume. The giant brain gyrus is firstly reduced by the cerebral gyrus. In severe cases, only the main cerebral gyrus can be found. The giant gyrus is often combined with no cerebral gyrus.

Giant brain return deformity examination

The giant brain is deformed, and the CT image shows the characteristic manifestation of widening the cerebral hemisphere cerebral gyrus, thickening of the cerebral cortex, smooth inner surface of the cortex, and thinning of white matter.

Diagnosis and diagnosis of giant brain gyrus

diagnosis

Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.

Differential diagnosis

Different from epilepsy.

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