Infantile fibromatosis of the fingers
Introduction
Introduction to infantile fingertip fibromatosis Infantile digital fibromatosis is rare and is a special myofibroblastic proliferation that occurs mainly in the fingers of the infant and young children. It is characterized by no tumor on the thumb and big toe, and histopathologically visible cytoplasmic eosinophilic inclusions. basic knowledge The proportion of illness: 1% of the specific population Susceptible people: children Mode of infection: non-infectious Complications: sepsis
Cause
Causes of infantile fibroid disease
(1) Causes of the disease
The etiology of this disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy.
(two) pathogenesis
The pathogenesis is still unclear. Pathological examination of the dermis shows a number of spindle-forming fibroblasts and bundles of collagen fibers arranged in a bundled shape that can be extended to subcutaneous tissue. Many fibroblasts have special eosinophilic inclusions next to the nucleus, which is a diagnostic value.
Prevention
Infant fingertip fibromatosis prevention
The etiology of this disease is still unclear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. Therefore, this disease cannot be prevented for the cause. Early detection, early diagnosis, and early treatment are important for indirect prevention of this disease, and can also reduce the incidence of infection complications. For patients with existing infections, antibiotic rubbing and systemic treatment should be given as soon as possible.
Complication
Infant phalangiofibromatosis complications Complications sepsis
The main complications of this disease are related to skin damage. Because this disease is often accompanied by itching, the child often scratches and the skin integrity is destroyed. Therefore, the patient may scratch the skin to induce bacterial infection or fungal infection, usually secondary to low body constitution. Or long-term use of immunosuppressive agents and fungal infections such as onychomycosis, such as concurrent bacterial infections may have fever, skin swelling, ulceration and purulent secretion and other performance. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Infant fingertip fibromatosis symptoms Common symptoms Repeated infection of the skin Itching nodules Finger (toe) A transverse finger sausage type
Common in infants less than 1 year old, 1/3 occurred in the first birth, the lesion is usually single or several solid red smooth nodules, about 1cm in diameter, no symptoms, good to the distal finger (toe The back and sides, the thumb and the big toe are not infringed, and the damage does not transfer.
Examine
Infant fingertip fibromatosis examination
Histopathology: The dermis sees many shuttle-forming fibroblasts and bundles of collagen fibers arranged in a bundled shape, which can be extended to the subcutaneous tissue. Many fibroblasts have special eosinophilic inclusion bodies next to the nucleus, which is a diagnostic value. It was purple when stained with phosphotungstic acid hematoxylin and stained dark red or Masson.
Diagnosis
Diagnosis and identification of infantile finger fibroma
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
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