Pediatric Bilip Syndrome

Introduction to children's double lip syndrome Laffer-Ascherssyndrome is also known as goiter and double-lip syndrome orbital relaxation syndrome, Laffer-Ascher syndrome, Ascher syndrome. In 1909, Laffer first reported a case of lip and eyelid sag. Later, Ascher found the third symptom, non-toxic goiter. Therefore, foreign scholars refer to the double-lip-eyelid sagging-non-toxic goiter triplet as Laffer-Ascher syndrome. basic knowledge Sickness ratio: 0.05%-0.06% Susceptible people: children Mode of infection: non-infectious Complications: septic shock

The cause of children's double lip syndrome

Causes:

The etiology of this disease is not clear. Some people think that it is related to the genetic factors such as traumatic endocrine disorders or related to the instability of autonomic nervous system in rheumatoid diseases.

Pathogenesis

The pathogenesis remains to be further studied.

Pediatric double lip syndrome prevention

At present, the cause is unknown, and there are no targeted preventive measures. Early detection, early diagnosis and early treatment are of great significance in preventing this disease.

Pediatric double lip syndrome complications Complications septic shock

When the endocrine disorder reaches the body's resistance, the disease is easy to be complicated by infectious diseases.

Infectious diseases are caused by other diseases during the treatment of patients due to their poor constitution and resistance to pathogens. That is, if the wound is not well protected after surgical treatment of the disease, and it is easy to be infected and not easy to heal without paying attention to disinfection and protection of the knife edge.

Symptoms of Pediatric Lip Syndrome Common Symptoms Goiter, lower lip swelling, valgus, eyelid relaxation, upper lip thickening, single lateral atrophy, horn dysplasia

Clinical features:

1. Lip lesions: It can be a discontinuous episode at the beginning, and then it can be converted into persistent swelling. It is often seen that the upper lip is swollen or the upper and lower lips are involved at the same time. Because the upper lip mucosal transition part is swollen and sagging, especially in the speech, it is like a double lip called the double lip syndrome.

2. Orbital lesions: The symptoms of early onset of the disease are generally divided into two stages. At the beginning of the eye, angioedema of the eyelids was repeated, and the skin of the eyelids became thinner and atrophied.

3. Goiter: more than a few years after the occurrence of eyelids and lip lesions, only about 20 to 30 years old.

4. Others: There are symptoms such as facial skin pigmentation and mild atrophy of the facial side.

Examination of children's double lip syndrome

1. Routine examination, routine examination, observation of the presence of thyroid abnormalities, eyelid lesions and lesions of the lips.

2. Immunological examination and endocrine examination, seven tests of thyroid function, to see if there is thyroxine function.

3. Doppler ultrasonography, scanning examination, to observe the presence or absence of goiter and its nature, while eliminating other diseases of the thyroid.

Diagnosis and diagnosis of children's double lip syndrome

diagnosis

1, the diagnosis of this disease is mainly based on typical clinical manifestations.

2, pathological examination: visible lip mucosal tissue edema, perivascular inflammatory cell infiltration.

3, laboratory tests: no abnormalities in routine, erythrocyte sedimentation rate, rheumatoid factor, etc.

Differential diagnosis

Pediatric double-lip syndrome should be differentiated from allergies at the beginning.

Allergies are physiological reactions in which sudden and rapid abnormalities occur when the human body comes into contact with or injects a special antigen that is not excessive and can withstand.

Most patients start skin flushing with skin symptoms and often accompanied by sweating erythema and itching, especially in the hands, feet and groin, allergic rhinitis in the nose, redness and itching in the eyes.

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