Segmental hyaline vasculitis

Introduction to segmental transparent vasculitis Segmental hyalinaritis (segmentalhyalinizingvasculitis) is a vasculitis disease in which atrophic scars are left after the occurrence of pleomorphic skin lesions on the basis of small vascular lesions of both lower extremities. This disease occurs mostly in young and middle-aged women. Most cases are exacerbated in summer, and the opposite is less in winter. basic knowledge Sickness ratio: 0.00045% Susceptible people: no special people Mode of infection: non-infectious Complications: vasculitis

The cause of segmental transparent vasculitis

Cause:

It may be related to immune abnormalities, and it is different from leukocyte fragment vasculitis because there is very little neutrophil infiltration and nuclear dust in tissue lesions.

The dermal endothelial cells proliferate, and some of the venous endothelial cells proliferate in the superficial interval of subcutaneous fat tissue. The wall is thickened by eosinophilic deposition, transparent thrombus is formed in the lumen, and red blood cells around the blood vessels leak out, mainly lymphocyte infiltration. Occasionally, neutrophils and nuclear dust, epidermal acanthosis cells are mildly hypertrophic, or vacuolar degeneration and necrosis.

Segmental transparent vasculitis prevention

Vasculitis is very common in the clinic and occurs mostly in young people. It may be accompanied by multiple systemic damage, or ischemic or blood stasis symptoms and signs. The lesions are uplifted purpura and other nodular necrotizing rashes. Some symptoms may also be accompanied by fever. If you want to stay away from the disease as soon as possible, you should start from prevention, early diagnosis, early treatment, as far as possible to find the pathogen, and the key to treatment and prevention.

Segmental transparent vasculitis complications Complications vasculitis

After the lesion of the lesion is absorbed, the underlying tissue can be atrophied into a white atrophic scar.

Atrophic scars are scars named after the dysfunction that they cause. More common after deep burn healing, due to scar contraction, often lead to shape changes and dysfunction, long-term scar contracture can affect the development of bones, muscles, blood vessels, nerves and other tissues, should be treated early. Clinically common deformities caused by scar contracture include valgus valgus, lip valgus, chest-thoracic adhesion, hand scar contracture deformity, and flexion or atrophic scar extension and contracture deformity of each joint.

Segmental transparent vasculitis symptoms common symptoms freckle twitch reticular plaque

The damage of this disease is first seen in the lower part of the lower leg, especially the internal and external iliac crest and its surroundings, and then slowly up to the upper part of the knee joint, down to the back of the foot, the toe end and the sole of the foot, the primary damage is a bright red spot with a large needle. Patches that are ring-shaped or densely dense, such as large fingers, the central part of the sputum gradually becomes dark purple-red ecchymoses, further forming black sputum, sometimes thick, surrounded by gray blisters, loose blisters, underarms are mung beans To the size of soy beans, the shape is irregular, the edges are not neat, the pain is the most painful when staling purple, and can be twitching, sometimes only pale red localized bulge, pain and tenderness are also significant, ulcer healing is slow, Left a yellowish atrophic scar, or only pale yellow pigmentation spots, while a little white atrophic scar scattered in the middle, the ulcer is mainly in the lower leg and internal and external sac, the course of the disease is chronic, repeated attacks, the elderly are 5 More than half of the patients have reticular bluish spots in the lower part of the lower thigh after 1-3 years of calf incidence, and appear in winter or cold, disappearing in warm and summer, but not developing into organic lesions. After the leg heal damage, Livedo not disappear.

Segmental hyaline vasculitis

Mainly based on clinical manifestations and histopathological examination confirmed.

Generally no positive findings. Hematuria, platelet count and suspected blood time, erythrocyte sedimentation rate, immunoglobulin, circulating immune complex, C2, C3 and C4, CH50 rheumatoid factor, antinuclear factor, protein electrophoresis, fibrinogen determination and HBsHg examination, etc. Angiography, Doppler ultrasonography, and X-ray examination should be performed as needed.

Histopathology: Epidermal atrophy, V-shaped necrotic area visible in the epidermis and upper dermis. The vessel wall is thickened, fibrin-like substances are deposited in the wall and lumen, the lumen is partially or completely occluded, and red blood cells overflow. There are lymphocytes and histiocytes infiltrated around the tube.

Diagnosis and differentiation of segmental transparent vasculitis

Pay attention to the identification of reticular bluish.

Reticular leukoplakia is a vascular disorder of the skin that is caused by a variety of causes. A persistent cyanotic network change in the skin is a clinical feature. When the long-lasting functional vascular changes develop into organic lesions, it is called reticular plaque vasculitis, and the disease is rare in clinical practice. This disease belongs to the category of "blood stasis syndrome" of traditional Chinese medicine. Some people think that this disease is a "catch".

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