Skin dysplasia

Introduction to skin dysplasia Alplasiacutis, also known as congenital skin defects, is a congenital defect in the epidermal dermis, sometimes even in the subcutaneous tissue, in one or several regions. basic knowledge Sickness ratio: 0.1% Susceptible people: no special people Mode of infection: non-infectious Complications: Pediatric hereditary bullous epidermolysis

Cause of skin dysplasia

(1) Causes of the disease

It is autosomal dominant or recessive, and may also be associated with defects in primary differentiation and adjacent amniotic developmental defects.

(two) pathogenesis

The pathogenesis is not well understood and may be associated with defects in primary differentiation and adjacent amniotic membrane developmental defects.

Skin dysplasia prevention

There are no effective preventive measures, and early detection and early treatment are the key to prevention.

Skin dysplasia complications Complications Pediatric hereditary bullous epidermolysis

May be associated with other developmental abnormalities, such as congenital amputation, most patients with bullous epidermolysis.

Symptoms of dysplasia common symptoms crusting granuloma

At the time of birth, there is a well-defined skin defect, the base is rough, and the red granuloma is a large thick-walled bullae. The top of the skin is quickly shed, and the scalp defect is about 60%, generally 2cm, which can be as large as 9cm. Long, triangular, star-shaped, defect wound healing is slow, can be repeatedly scarred, falling off for months or even years, may be accompanied by other developmental abnormalities, such as congenital amputation, most patients with bullous epidermium Solution.

Skin dysplasia check

Histopathology: showing poor regeneration, varying depth, epidermis, loss of dermis structure, partial or total loss of fat in subcutaneous tissue, and no appendage after epidermal growth.

Diagnosis of skin dysplasia

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

Sometimes it can be confused with the forceps trauma, but it can be diagnosed from its shape, location and clear piercing edge. The epidermis should also be identified.

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