Cutaneous B-cell lymphoid nodular hyperplasia

Introduction to skin B-cell lymphoid nodular hyperplasia Skin B-cell lymphoid hyperplasia, nodular type is usually idiopathic, idiopathic B-cell lymphoid hyperplasia, formerly known as Speigler-Fendt sarcoidosis. basic knowledge The proportion of illness: 0.002% Susceptible population: women are three times as many as men, and 2/3 of patients are under 40 years old Mode of infection: non-infectious Complications: Mildew

Cause of skin B cell lymphoid nodular hyperplasia

Causes include tattoos, infection with Helicobacter pylori, herpes zoster, scars, antigen injections or acupuncture, and occasionally drug reactions and persistent insect bites.

Skin B cell lymphoid nodular hyperplasia prevention

No special preventive measures for the disease Early detection and early diagnosis is the key to the prevention and treatment of this disease:

1, first of all to pay attention to the health of the skin, especially in this hot summer, must take a bath, change clothes frequently. In summer, the weather is hot and the capillaries are dilated. If you don't pay attention to the bacteria, it is easy to invade.

2, the newly bought clothes are best washed first with laundry detergent or disinfectant, put it under the sun to dry and then wear. When the fabric is bleached, a large amount of chemical agent remains, and if it is not washed, it is easy to infect the skin cells.

3, usually pay attention to the diet, especially those who are allergic, eat less spicy and irritating food, shrimp and crabs such seafood as little as possible.

Skin B-cell lymphoid nodular hyperplasia complications Complications

Most of the disease is asymptomatic and lacks corresponding signs. At present, there are no reports of complications. Therefore no treatment is needed.

Skin B-cell lymphoid nodular hyperplasia symptoms common symptoms nodular papules

Idiopathic and secondary localized lesions are evacuated and firm skin papules or nodules, clustered or fused into plaques, mainly on the face, especially the buccal and nasal or earlobe, and secondly, the damage can invade the torso ( 36%) or limbs (25%), the nodular surface is usually smooth, flesh-colored, brownish yellow, red or purple, women's patients are three times as many as men, and 2/3 of patients are under 40 years old, disseminated or pan The rare cases are miliary papules. The lymphoid hyperplasia caused by infection with B. burgdorferi is not common. The damage occurs at the edge of the tick bite or immediately adjacent to the migratory erythema. The damage is up to 10 years after infection. Months appear, the lesions are multiple nodules, diameter 1 ~ 5cm, good invasive earlobe, nipple and areola, nasal and scrotum, usually no symptoms, may be associated with local lymphadenopathy, diagnosis can be based on tick bite history or Migratory erythema, predilection sites (lobe or nipple) and histopathological findings can be confirmed by an increase in anti-B. burgdorferi antibodies (in 50% of cases) and in the diseased tissues.

Examination of skin B-cell lymphoid nodular hyperplasia

Histopathology: dense dense nodular infiltration, mainly in the dermis; deep infiltration of the dermis and subcutaneous tissue, with a slight head and foot, a transparent boundary between the infiltration and the epidermis, mainly infiltrated by mature small and large lymphocytes, tissue It consists of cells, plasma cells and eosinophils. In the deep, the germinal center is clearly defined. The center is a large lymphoid cell. It is rich in cytoplasm and macrophages, surrounded by sleeve-like lymphocytes.

Diagnosis and differentiation of skin B-cell lymphoid nodular hyperplasia

According to clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed. The diagnosis can be confirmed by the increase of anti-B. burgdorferi antibody (in 50% of cases) and the discovery of DNA of the Helicobacter pylori in diseased tissues.

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