Desmoplastic piloepithelioma

Introduction to connective tissue proliferative hair epithelioma The connective tissue proliferative epithelioma (desmoplastictrichoepithelioma) was previously considered to be a single hair epithelial tumor, but it has sufficient clinical and histological features and is therefore considered to be a special type of hair epithelial tumor. Single or multiple lesions, often located in the face, 3 to 8 mm in diameter, markedly hardened, most of the edges are high, ring-shaped, central depression, no rupture, and thus with ring granuloma and plaque-like basal cells Cancer is similar, more common in adolescents, more women than men. basic knowledge The proportion of illness: 0.002% Susceptible people: more common in teenagers Mode of infection: non-infectious Complications: skin cancer

Connective tissue proliferative hair epithelioma

The tumor is located in the dermis with a clear border and is connected to the epidermis. The disease has three characteristics:

1 The tumor cells are arranged in a thin bundle, without large agglomerates. The bundles are usually 1 to 3 layers thick and composed of small basal cells. The nucleus is oval and has little cytoplasm. It tends to the dermal papilla and hair bulb. And hair root sheath differentiation, but can not differentiate into true hair follicles.

2 usually have a lot of keratinous cysts, some are larger, but generally small, the center can contain shadow cells. Foreign body granuloma can be seen at the destruction or calcification of the cyst.

3 interstitial tissue hyperplasia, containing a large amount of dense collagen, and less tumor tissue components.

Connective tissue proliferative hair epithelioma prevention

Usually try to reduce the mechanical, chemical, thermal stimulation of the affected area, underwear is best to wear pure cotton products, try to avoid repeated traction, friction, ulceration, infection. Hair Epithelial Tumor This tumor line originates from a benign tumor of the hair. It is generally believed that this disease may originate from pluripotent basal cells and is a benign tumor that differentiates into hair structure. The degree of differentiation is higher than that of basal cell epithelial tumors. Early detection and early diagnosis are the key to the prevention and treatment of this disease.

Connective tissue proliferative hair epithelioma complications Complications skin cancer

Connective tissue proliferative hair epithelioma can be complicated by hair follicles and sebaceous gland differentiation of tubular tubular adenomas; hair follicle differentiation can be seen as basal-like cells aggregated in a strip, surrounded by a matrix similar to the sheath surrounding the embryonic hair follicle. Some basal-like cell clusters are adjacent to obese fibroblast clusters, similar to degenerating hairy nipples. Many small lumens are surrounded by a large number of eosinophils in the aggregated cell strip. In the other case, the hair follicle differentiation showed a funnel-like structure formed by the isthmus epithelium, which was scattered in the differentiated mature sebaceous gland cells. In addition, some pathological changes in the lesion site suggest a connective tissue proliferative hair epithelioma.

Connective tissue proliferative hair epithelioma symptoms Common symptoms Dry hair and easy to break hard spot hardening ring granuloma

Single or multiple lesions, often located in the face, 3 to 8 mm in diameter, markedly hardened, most of the edges are high, ring-shaped, central depression, no rupture, and thus with ring granuloma and plaque-like basal cells Cancer is similar, more common in adolescents, more women than men.

Examination of connective tissue proliferative hair epithelioma

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Histopathology: three histological features: tumor cell bundle stenosis, horn cyst and connective tissue proliferative interstitial, tumor cell bundle 1-3 cells thick, composed of small basal cells, the latter nucleus oval The cytoplasm is not abundant; there are often many horn cysts, some have large horn cysts; there are few interstitial cells and quite dense collagen, no large tumor cells, and some horny cysts have calcification.

Diagnosis and diagnosis of connective tissue proliferative hair epithelioma

In the past, this disease was considered to be a single hair epithelial tumor, but it has sufficient clinical and histological features and is considered as a special type of hair epithelial tumor. The disease is also known as sclerosing epithelial hamartoma, but it is still preferable to connective tissue proliferative hair epithelioma, so the name can emphasize the relationship between this disease and single hair epithelial tumor. Skin lesions are common in the face, especially the perioral, single-shot, 3 to 8 mm diameter papule clusters integrated annular plaques, yellowish white, the base has obvious induration, most of the damage edge ridges, linear dykes, central depression, It does not rupture, so it is similar to ring granuloma, which is most common in early childhood, but it is not uncommon for people in their teens to have more women.

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