Measles-like erythema
Introduction
Measles-like erythema Measles-like erythema (erythemamorbilliforme) is an acute systemic erythema. It usually has chills, fever, headache and other systemic symptoms before the onset, often accompanied by itching. basic knowledge The proportion of illness: 0.002% Susceptible people: no special people Mode of infection: non-infectious Complications: pruritus, onychomycosis, swelling
Cause
Measles-like erythema
(1) Causes of the disease
The cause is unknown, and some cases are related to drug allergy (barbiturate, penicillin, amalgam, salicylate, etc.).
(two) pathogenesis
The pathogenesis is unknown, and some cases are related to drug allergy.
Prevention
Measles-like erythema prevention
The disease is related to allergic factors and is also related to the use of drugs. Most drugs have the possibility of causing drug eruptions, including Chinese herbal medicines, but most of them are caused by more antigenicity. Mostly antipyretic analgesics, barbital, penicillin, streptomycin, sulfonamide and so on. In addition, for patients with congenital allergic diseases and patients with diseases of vital organs, the risk of drug eruption is relatively high. Therefore, the prevention of this disease is mainly to avoid the use of allergic drugs.
Complication
Measles-like erythema complications Complications, pruritus, gray nails, swelling
The disease is usually accompanied by itching of the skin, the patient often scratches the skin, and the abnormal keratinization of the skin can cause the skin integrity to be destroyed, so the skin bacterial infection or fungal infection can be induced by the patient's scratching, usually secondary to low body, or long-term. Patients with immunosuppressive agents and fungal infections such as onychomycosis, such as concurrent bacterial infections, may have symptoms such as fever, swelling of the skin, ulceration, and purulent secretion. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Measles-like erythema symptoms Common symptoms Measles face fever, itching, maculopapular rash, skin bleeding, chills
Sudden onset, often accompanied by chills, fever and other systemic symptoms, the rash begins to be red, the cap needle to the large grain of the papules, and then gradually develop into a macula or maculopapular rash, which turns dark red after the beginning of the red, can be integrated with each other. Symmetrical distribution, can be generalized to the whole body, obvious to the trunk, similar to measles, and later spread to the limbs and face, mucosal erythema may occur, accompanied by moderate to severe itching, severe cases may be associated with small bleeding points, rash usually lasts 1 to 2 Week, after the rash gradually subsided, about 2 to 3 weeks after the complete disappearance, usually without visceral damage, if the rash caused by the drug, did not stop in time, can be developed to severe drug rash.
Examine
Measles-like erythema examination
Histopathological examination: sparse lymphocytes infiltrated around the superficial vascular plexus, and a few vacuoles appeared at the junction of the epidermal dermis.
Diagnosis
Diagnostic identification of measles-like erythema
According to its typical clinical manifestations and medical history can be diagnosed.
Need to be identified with scarlet fever, measles, toxic shock syndrome, staphylococcal scarlet fever.
1. Scarlet fever: an acute respiratory infection caused by group A hemolytic streptococcal infection, its clinical features are fever, angina, diffuse red rash and diffuse smear after sputum retreat, a small number of patients due to illness Abnormal reactions occur in the heart, kidney, joint damage.
2. Toxic shock: A syndrome caused by staphylococcal exotoxin characterized by high fever, vomiting, diarrhea, confusion, and rash that can quickly progress to severe and refractory shock.
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