Transient pustular melanosis of the newborn

Brief introduction of neonatal transient pustular melanosis Transientneonatal pustular melanosis is a transient aseptic impetigo that occurs in newborns and leaves pigmentation after regression. basic knowledge The proportion of illness: 0.0035% Susceptible people: infants and young children Mode of infection: non-infectious complication:

Causes of transient pustular melanosis in newborns

(1) Causes of the disease

The cause is unknown, no bacteria or viruses are seen in the pustules, and the relationship with the drugs is still unclear.

(two) pathogenesis

The pathogenesis is still unclear.

Neonatal temporary pustular melanosis prevention

Keep room temperature at 24 ~ 26 ° C, humidity 55 ~ 60%, indoor air is fresh, sunny, 2 times a day ventilation, pay attention to avoid convective wind. Bathe and change clothes every day, gentle movements during bathing, and clean skin wrinkles. Choose loose, soft cotton clothes, change your diaper and keep your body clean.

Neonatal transient pustular melanosis complications Complication

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Neonatal transient pustular melanosis symptoms common symptoms scaly pustules red herpes herpes scars

Occurred in the newborn, the lesions are located on the cheek, frontal, neck, lower back and buttocks, pustules or blisters pustules, no redness around, diameter 0.1-0.3cm, neckline scaly around the pustule rupture, central pigmentation, Pustules dry and crusted after 1 to 2 days, most of which leave pigmentation, which lasts for weeks to months, no systemic symptoms, skin lesions can also be seen in the head, palmar and lower abdomen, and neutrophils in the pus Cells, cultured without bacterial growth.

Examination of neonatal transient pustular melanosis

There are neutrophils in the pus, and there is no bacterial growth in the culture.

Histopathology: The pustule is located in the horn layer or under the horn layer, contains more neutrophils, a few eosinophils and keratinocyte debris, hyperkeratosis in the pigmentation, increased basal pigment, no in the dermis Melanocytes, focal lymphocytes and plasma cell infiltration.

Diagnosis and differentiation of neonatal transient pustular melanosis

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

Should be diagnosed with neonatal impetigo, neonatal toxic erythema.

1. Neonatal toxic erythema often occurs 1 to 2 days after birth, on the trunk, rarely involving the face, the damage is diffuse erythema, no pigmentation spots, and eosinophils in the lesions.

2. Neonatal pustulosis pus bacterial culture and smear positive.

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