Felty syndrome

Introduction to Felty Syndrome Felty syndrome is also known as arthritis-neutropenia-splenomegaly syndrome, rheumatoid arthritis-splenomegaly syndrome, and infectious arthritis. The cause is unknown and may be an autoimmune disease. In 1924, Flety first reported adult chronic rheumatoid arthritis with neutropenia and splenomegaly. Since then, it has been reported frequently that the disease with the above three major characteristics is called Flety syndrome. basic knowledge The proportion of illness: 0.002% Susceptible people: no special people Mode of infection: non-infectious Complications: amyloidosis

Cause of Felty Syndrome

The pathogenesis of this disease may be related to immune complex-mediated damage to venules caused by secondary liver injury. Although some people think that leukopenia is caused by hypersplenism, some patients have leukopenia after splenectomy. It cannot be corrected.

Felty syndrome prevention

The disease is an autoimmune disease, and there is no special prevention method. Physical exercise should be strengthened to increase self-immunity.

Felty syndrome complications Complications amyloidosis

Rheumatoid arthritis with Felty syndrome, Sjogren syndrome or amyloidosis is more likely to be associated with liver disease.

Symptoms of Felty Syndrome Common Symptoms Splenomegaly Attenuated Anorexia Fever

This disease is a special type of rheumatoid arthritis. It usually occurs after months or even years of arthritis. It can have:

1. General malaise, fever, fatigue, anorexia, weight loss.

2. Brown pigmentation appears on the exposed skin, very black.

3. Skin or mucosal ulcers, especially small leg ulcers.

4. Splenomegaly, individual spleen.

5. Some patients have swollen lymph nodes, purpura and repeated infections.

Examination of Felty syndrome

1. Red blood cells in the bone marrow are moderately proliferated in each system, and granulocyte maturation is impaired.

2. Blood: moderately hypochromic anemia, mild reduction of platelets, and significant reduction of neutrophils. In severe cases, it can be <1×109/L; lymphocytes have no obvious changes.

3. The lupus erythematosus cell test was negative, the Coombs test was negative, and the RF latex agglutination test was often positive.

Diagnosis and diagnosis of Felty syndrome

Diagnosis can be based on medical history, clinical manifestations, and laboratory data.

This disease should be distinguished from rheumatoid arthritis.

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