Shunt hyperbilirubinemia syndrome

Introduction to shunt hyperbilirubinemia syndrome The shunt hyperbilirubinemia syndrome, Israel syndrome, is caused by excessive production of bilirubin by bone marrow red blood cells or precursors, or directly by the destruction and production of erythroline or tetrapyrrole precursors. Both men and women can suffer from the disease, 10 to 20 years old, with jaundice and splenomegaly, blood examination for spherical red blood cells and increased erythrocyte fragility, reticulocyte red increase, indirect hyperbilirubinemia, increased urinary biliary excretion, Free dissolution and mechanical fragility, normal liver function. basic knowledge The proportion of illness: 0.003% Susceptible people: no special people Mode of infection: non-infectious complication:

The cause of shunt hyperbilirubinemia syndrome

Excessive bilirubin produced by bone marrow red blood cells or precursors, or directly caused by destruction and production of erythroline or tetrapyrrole precursors.

Divided hyperbilirubinemia syndrome prevention

Active prevention of hepatobiliary diseases is the basic preventive measure of this disease.

Divided complications of hyperbilirubinemia syndrome Complication

Biliary malformations, central nervous system damage, bilirubin encephalopathy, etc.

Symptoms of shunt hyperbilirubinemia syndrome Common symptoms Urinary biliary excretion increases diarrhea, bloating, nausea, jaundice, indigestion

Both men and women can suffer from the disease, 10 to 20 years old, with jaundice and splenomegaly, blood examination for spherical red blood cells and increased erythrocyte fragility, reticulocyte red increase, indirect hyperbilirubinemia, increased urinary biliary excretion, Free dissolution and mechanical fragility, normal liver function.

According to clinical features and laboratory tests can be diagnosed, but liver biopsy is required to confirm the exclusion of other types of congenital jaundice.

Examination of shunt hyperbilirubinemia syndrome

Blood tests showed increased spherocytosis of red blood cells and red blood cells, moderate increase in reticulocytes, indirect hyperbilirubinemia, increased urinary excretion, free dissolution and normal mechanical fragility, and normal liver function.

Blood tests, liver tissue biopsy.

Diagnosis and diagnosis of shunt hyperbilirubinemia syndrome

Need to be distinguished from other types of jaundice.

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