Enemy rat poisoning
Introduction
Introduction to enemy poisoning Diphacinone is a new type of anticoagulant rodenticide, which is a highly toxic type. Currently, it is commonly used in 1% enemy mouse powder and 1% enemy sodium salt. Pediatric poisoning is caused by improper placement of this type of poisonous rat medicine, which is caused by self-contained swallowing; or contamination of the food and poisoned livestock by accidental consumption. basic knowledge The proportion of sickness: 0.01% Susceptible people: no specific population Mode of infection: non-infectious Complications: nose bleeding, hematuria, cerebral hemorrhage
Cause
Enemy poisoning cause
After the enemy rats enter the body, the activity of vitamin K is reduced mainly by competitive inhibition, which hinders the liver from synthesizing prothrombin and some blood coagulation factors, and plays an anticoagulant effect, thus exhibiting bleeding in various parts; this product can damage the capillary In the blood vessel wall, aseptic inflammation changes, which increases the permeability and fragility of the wall and aggravates the bleeding tendency.
Prevention
Enemy mouse poisoning prevention
Properly preserve the poisonous rat medicine; the area where the bait is placed should be strictly guarded, and the daytime collection; the poisoned birds and livestock must be buried or cremated.
Complication
Enemy mouse poisoning complications Complications, hemorrhagic cerebral hemorrhage
The main complication is extensive hemorrhage, first hematuria, nose bleeding, gum bleeding, subcutaneous hemorrhage, severe hemoptysis, vomiting blood, blood in the stool and other important organ hemorrhage, can be complicated by shock, often died of cerebral hemorrhage, myocardial hemorrhage.
Symptom
Symptoms of poisoning of enemy mice Common symptoms Nasal hair stun coma bleeding tendency gums bleeding appetite decreased blood hemoptysis bloody abdominal pain
Symptoms such as nausea, vomiting, loss of appetite, lack of energy, abdominal pain, low back pain, joint pain, etc. occur shortly after eating, such as nausea, vomiting, low back pain, joint pain, etc.; Purpura, hemoptysis, blood in the stool, blood in the urine, etc.; if the bleeding is severe, it may cause shock due to ischemia and hypoxia. If there is bleeding in the heart, brain, etc., and the corresponding symptoms may occur, the child may have cyanosis, convulsions, coma, enlarged pupils or unequal size. For children with a history of toxic poisoning and a tendency to show bleeding, they should be examined, clotting time, prothrombin time, if necessary, prothrombin time correction test, the patient's platelet count can also be reduced, beam arm test is positive . At the same time, suspicious drugs, food, vomit, and stomach contents were taken for toxicant identification.
Examine
Enemy poisoning check
Rapid detection of vomiting enemy mice by poisoning personnel: The method used anhydrous ethanol to extract the enemy mice in the vomit and quantified by the reaction of ferric chloride. The detection limit was 0.020g/kg, the linear range was 02mg/10ml, the correlation coefficient was r=0.9991, the coefficient of variation was 4.6%8.1%, and the recovery was 90%105%. Conclusion This method is accurate and fast, and can be applied to on-site inspection.
Diagnosis
Diagnosis and identification of enemy mice poisoning
If there is abdominal pain and bleeding tendency, it should be checked in time for bleeding and coagulation, and the urine should be checked for toxicity to confirm the diagnosis.
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