Green tumor

Introduction to green tumor A green tumor is a localized infiltration of myeloid leukemia, abnormal white blood cells in the subperiosteal or soft tissue. Because of its light green color (the pale green pigment in the tumor cell protoplasmic bone), the tumor has a rounded bulge like a tumor, hence the name. Most of the patients with this disease are healthy children. Men are more common than women. The blood and bone marrow of leukemia often change. The course of disease is rapid and rapid, and it can die within months or even weeks. basic knowledge The proportion of illness: the incidence rate is about 0.003% - 0.004% Susceptible people: good for children and adolescents Mode of infection: non-infectious Complications: edema, swelling, leukemia, chronic myelogenous leukemia

Cause of green tumor

The green tumor is myeloid leukemia, which is mainly characterized by hyperplasia of the bone marrow, which results in the accumulation of a large number of medullary cells, thereby forming a tumor-like change.

Ionizing radiation (20%)

Ionizing radiation has a leukemia effect. Its effect is related to the size of the radiation dose and the location of the irradiation. A large dose or multiple small doses of radiation have the effect of causing myeloid leukemia, a green tumor. Patients with ankylosing spondylitis who receive X-ray therapy will also have an increased incidence.

Chemical substance (20%)

The role of benzene-induced leukemia has been widely recognized in the medical community. The long-term close contact with organic solvents has increased the risk of green tumors. A group of epidemiological surveys in China have shown that the risk of benzene workers in the production of benzene plants is 5 ~ 6 times.

Genetic factors (5%)

Genetics has been shown to be one of the important risk factors for green tumors. After one of the single-oval twins, their siblings have five times more chance of developing a green tumor within one year than the normal population.

Green tumor prevention

Do not touch X-rays and other harmful radiation too much. Personnel engaged in radiation work should do personal protection and strengthen preventive measures. Infants and pregnant women are more sensitive to radiation and vulnerable to injury. Women should avoid exposure to excessive radiation during pregnancy, otherwise the incidence of green tumors in the fetus is higher. However, the occasional, medical x-ray examination, the dose is small, basically does not affect the body. Keep away from radiation, infrequently dye hair, do not abuse drugs, eat less processed foods, and not overworked.

Green tumor complications Complications, edema, swelling, leukemia, chronic myelogenous leukemia

1. The eyelid mass often adheres to the gingival margin and the eyelid skin, which may be accompanied by eyelid and conjunctival edema, which is similar to inflammation, and can invade the paranasal sinus and cranial cavity. If the humerus is involved, the swelling of the tibia may produce a green surface, called a frog face.

2. Most patients with early symptoms of acute myeloid leukemia, a small number of patients with symptoms of chronic myelogenous leukemia, peripheral blood or bone marrow puncture confirmed granulocyte leukemia.

Symptoms of green tumors Common symptoms Eyelid swelling and pale green eyeballs protruding submandibular lymph nodes swelling tenderness bone marrow changes

This disease is highlighted by eyeballs. This is because the periosteum of the eyelid is a good site for localized infiltration of leukemia. Usually, the hard mass of the eyelid is touched. The eyelids are swollen and pale green, and the mass development is abnormally rapid. It can fill the eyelids, which involve the sinus and brain. The lymph nodes in the ear and the submandibular bone are often swollen. The surface of the skin also has green pigmentation. In the later stage of the disease, all the important organs and limbs are involved. In the late stage, the anemia is often caused by infection. death.

1. Green tumor is a special type of acute granulocyte leukoma. It occurs in children and adolescents. It is mainly in healthy children before the age of 12, males are more than females. The ratio of male to female is about 5.8:1. The younger the age, the higher the mortality rate. Can occur in any organ and tissue of the human body, often combined with intracranial invasion.

Second, but the central nervous system, eyelids and bone marrow are the most common. In the eyelids, most of the eyes are affected at the same time or successively, but it can also be caused by the confined eyelids for a long time. The typical manifestations are eyeballs and eyelid masses as the first symptom. This is because the tissues in the eyelids are infiltrated by white blood cells. Occurrence of the eyeball, sometimes infiltration to form a localized mass, located in the shallow part of the eyelid or near the ankle can touch the hard nodular mass of the texture, closely connected with the tibia, can not move, no tenderness, eccentric deviation or eye movement Restricted and eye pain.

Third, the lesion location is located in the upper part of the iliac crest, there may be destruction of the corresponding part of the humerus, clinically can be combined with subcutaneous, conjunctival or fundus hemorrhage, the domestic literature reported that the liver, spleen, lymph nodes are swollen.

Green tumor examination

The blood and bone marrow of leukemia often change, and the course of disease is rapid and rapid, and can die within months or even weeks.

Leukemia examinations include:

Cytogenetic examination: This leukemia test also needs to pump about 2 ml of bone marrow to understand the nature of the leukemia cells and whether the chromosomes are abnormal. Leukemia with chromosomal abnormalities tends to be worse than leukemia without chromosomal abnormalities. This is the most important method of examination for leukemia.

Cerebrospinal fluid examination: This test is to take a cerebrospinal fluid test from the patient's lumbar spinal cord cavity to see if the patient's brain and spinal cord system (ie, the central nervous system) is attacked by leukemia cells. This is also one of the methods for examining leukemia.

Bone marrow routine examination: Bone marrow examination is the most common examination of leukemia. If leukemia is suspected, a bone marrow puncture must be performed to count and classify the various types of cells in the bone marrow.

Diagnosis of green tumor diagnosis

In the diagnosis of green tumors, clinical expression varies from person to person, and each is different. Imaging is also an indirect diagnosis, which is easy to be misdiagnosed. The decisive role is the diagnosis of pathological cytology and tissue immunology.

POX staining or MPO staining is positive on giant tumor cells, which is an important diagnostic indicator for green tumors.

Green tumor is a common malignant tumor in children. The orbital green tumor is a tumor-like infiltration of abnormal cells of granulocytic leukemia in the periosteum and orbital tissue. It is named after the fresh tissue section is green. It is more common for children under 10 years old. Males are more common than females, and most of them are simultaneous or sequential in both eyes. In the literature, 3476 cases of orbital space-occupying tumors accounted for 32 cases (5.09%) of green tumors, and 65 cases of leukemia patients with green tumors (4.6%). The diagnosis of a typical green tumor is not too difficult. As long as there is a subperiosteal green tumor in the clinic and the characteristics of leukemia, the bone marrow is confirmed to be granulocyte leukemia, which can be diagnosed, but the green tumor is rare in clinical practice and is easily misdiagnosed.

MR manifestations of sacral and craniofacial bones in children with metastatic neuroblastoma and green tumors are helpful for diagnosis and differential diagnosis.

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