Urinary bile acids

Bile acids evolve from cholesterol and are the main component of bile. It is the largest amount of organic acid secreted by the liver into the bile. Cholic acid and chenodeoxycholic acid synthesized by hepatocytes using cholesterol as a raw material are called protobiliary acids. After the bile is discharged into the intestine, it is produced by the intestinal bacterial plexase to produce deoxycholic acid and cholinic acid, respectively, which is also called secondary bile acid. The secondary bile acids are combined with glycine and taurine to form a primary binding bile acid and glycine chenodeoxycholic acid. 95% of the primary bile acids are reabsorbed at the end of the ileum. After the portal vein to the liver, the liver cells again After ingestion, it is stored in the gallbladder. When the food is digested, it is discharged into the intestinal cavity to digest the fat to form a hepatoenteral circulation. When liver cells are damaged or when the bile duct is damaged, it causes a change in bile acid. Total bile acid is a sensitive indicator of liver function. When there is only slight necrosis of hepatocytes, total bile acid can be increased, which is earlier than bilirubin and alanine aminotransferase (ALT), even earlier than liver tissue. See the biopsy. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Hepatic and obstructive jaundice caused by toxic hepatitis, toxic hepatitis, gallstones, etc. Tips: Do not exercise vigorously, heavy physical labor, stop taking diuretics, amphotericin B and other drugs. Normal value negative. Clinical significance Abnormal result Positive: Hepatocellular and obstructive jaundice caused by toxic hepatitis, toxic hepatitis, gallstones, etc. People who need to be tested Loss of appetite, poor digestion, abdominal distension after eating. Positive results may be diseases: gallstones, hepatitis, hepatitis B virus, elderly viral hepatitis precautions Before the test: prohibit strenuous exercise, heavy physical labor, stop taking diuretics, amphotericin B and other drugs. When checking: Relax your body and eliminate tension and anxiety. Not suitable for the crowd: no. Inspection process The urine of the examinee is collected and examined by chemical methods. Not suitable for the crowd Generally not. Adverse reactions and risks No.

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