Urinary weekly protein (BJP)

This week, the protein is a light chain mono- or dimer of immunoglobulin, which is an incomplete antibody globulin, which can be excreted from the urine when the plasma concentration is abnormally increased. The presence of this protein in the urine reflects the production of a large number of light chain portions of clonal immunoglobulin by malignant plasma cells. This week, the protein solidifies at 40-60 degrees Celsius, and dissolves when it is close to 100 degrees Celsius, so it is also called coagulating protein. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Positive: multiple myeloma (about 70%), amyloidosis, hyperparathyroidism, adult Fanconi syndrome (familial whole bone marrow atrophy syndrome), benign single cell line gamma globulin disease. Tips: Should be careful not to bring non-urine ingredients into the urine: such as female patients do not mix vaginal discharge and menstrual blood, male patients should not mix with prostatic fluid. Normal value Qualitative negative. Newborns can be weakly positive. Clinical significance Positive, more common in patients with multiple myeloma, a large number of this week's protein, the positive rate of up to 35% ~ 65%. The amount of protein this week reflects the number of monoclonal cells that produce this week's protein, which is meaningful for observing the course of myeloma and judging the effect of chemotherapy. This week, protein positive is also seen in benign monoclonal immunoglobulinemia, macroglobulinemia, amyloidosis, malignant lymphoma, chronic nephritis, metastatic cancer. Note that drugs such as aminosalicylic acid, chlorpromazine, and high-dose penicillin may cause false positives. Alkaline urine, severe urinary tract infections, etc. can have false negatives. Positive results may be diseases: primary monoclonal immunoglobulin disease, primary systemic amyloidosis, primary monoclonal globulin disease, renal damage considerations Send urine volume: generally 5 ~ 10ml. Fresh urine must be sent in time. Care should be taken not to bring non-urine ingredients into the urine: such as female patients do not mix vaginal discharge and menstrual blood, male patients should not mix with prostatic fluid. Inspection process Renal function test. Not suitable for the crowd There are no special taboos. Adverse reactions and risks There are no related complications and hazards.

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