cerebrospinal fluid calmodulin
CaM is an important calmodulin protein, which is widely present in all eukaryotic cells and has high affinity for ions. It is an intracellular receptor for calcium. Its main physiological functions are regulating the functions of the nervous system (including synthesis and release of neurotransmitters, synaptic transmission, axoplasmic transport and phosphorylation of proteins in the brain), various cell movements, muscle contraction and relaxation, and various Enzyme activity, synthesis and release of prostaglandins and insulin, and metabolism of glycogen. Basic Information Specialist classification: neurological examination classification: cerebrospinal fluid examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: normal. Normal value: Cerebrospinal fluid calmodulin: 0.01-0.75μg Above normal: The content of CaM in CSF increased in patients with cerebral infarction, and the increase was related to infarct size. negative: Positive: Tips: Patients or their families should follow the doctor's instructions. Normal value 0.38 ± 0.37 μg. Clinical significance Abnormal result The content of CaM in CSF increased in patients with cerebral infarction, and the increase was related to infarct size. Person who needs to be tested A person with a severe head injury. High results may be diseases: cerebral infarction, multiple cerebral infarction mental disorders Before the test: the patient needs to take a good rest and adjust the mentality. At the time of testing: the patient or family member should follow the doctor's instructions. Inspection process The patient's cerebrospinal fluid was drawn, and the cerebrospinal fluid calmodulin was extracted chemically and the amount was measured. Not suitable for the crowd 1. If there is obvious papilledema or cerebral palsy, contraindications are contraindicated. 2. Patients who are in shock, exhaustion or endangered state and local skin inflammation, and lesions in the posterior cranial fossa are contraindicated. Adverse reactions and risks If the patient has symptoms such as breathing, pulse, or abnormal color during puncture, stop the operation immediately and deal with it accordingly.
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