Multidrug Resistance (MDR) Genetic Testing

The multidrug resistance (MDR) gene encodes P-glycoprotein (P-170), which is located on the cell membrane and has a drug pumping effect. The drug that enters the cell is pumped out of the cell to make the cell resistant. MDR positive indicates multidrug resistance in various cancers. Basic Information Specialist Category: Oncology Inspection Category: Genetic Testing (DNA) Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Normal range: negative. Positive: Positive: 1. Determine whether the tumor patient is resistant to the current chemotherapy medication. 2. Guide clinical medication before chemotherapy to select or formulate chemotherapy. Tips: Check with your doctor. Normal value The normal range is negative. Clinical significance Positive: 1. Determine whether the tumor patient is resistant to the current chemotherapy medication. 2. Guide clinical medication before chemotherapy to select or formulate chemotherapy. Positive results may be diseases: malignant tumors, undifferentiated cancer of the parotid gland No absolute or relative contraindications. Inspection process Immunohistochemistry (IHC), immunofluorescence, and the like. Commonly used P-gp-specific monoclonal antibodies are JSB-1, MRK1, C219, U12, HYB-612, etc. Different monoclonal antibodies recognize different antigenic determinants, and the specificity and affinity of each monoclonal antibody are not completely the same. Not suitable for the crowd Taboo people: No. Adverse reactions and risks Generally no special complications.

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