Y chromatin

The long arm of the male Y chromosome is composed of heterochromatin distally, and strong fluorescence can occur when stained with a fluorescent dye. Staining with quinacrine or quin-acrine mustard, and then observing with a fluorescence microscope, strong fluorescence was observed at the long arm end of the human Y chromosome. This fluorescence is also easily seen in the nucleus during the division, so it is called Y chromatin or Y small body. Basic Information Specialist classification: growth and development check classification: genetic testing (DNA) Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: Negative is normal. Counting 100 cells, calculate the positive rate, Y body of male fetus>50%, more than 10% is judged as male fetus; female fetus of Y body accounted for 0% to 1%, less than 5% is judged as female fetus. Positive: Positive is an abnormal result. Tips: No special precautions. Normal value Counting 100 cells, calculate the positive rate, Y body of male fetus>50%, more than 10% is judged as male fetus; female fetus of Y body accounted for 0% to 1%, less than 5% is judged as female fetus. Clinical significance Clinical examination of Y bodies, also associated with X-linked genetic diseases, such as hemophilia, only in men, and women are carriers of pathogenic genes, other meanings can be found in the X-body examination section. In addition, the identification of hermaphroditism is also helpful. Y-small body of male pseudohermaphroditism is positive; Y body of XYY syndrome is double positive; Y body is congenital testicular hypoplasia positive; Y body of female pseudohermaphroditism is negative. Positive results may be diseases: male genital malformations, male infertility precautions No special precautions, check with your doctor. Inspection process Y chromatin (Y small body), blood smear specimens can be prepared by oral mucosal cells or earlobe, finger or venous blood, stained with the mustard quinine or sulphate hydrochloride dye, observed under a fluorescent microscope, see the inner edge of the nuclear membrane The small bright block with strong fluorescence is shaped like crescent, small spherical, etc., and has a diameter of about 0.25 μm, which is “Y small body”. Not suitable for the crowd Taboo people: No. Adverse reactions and risks Generally no special complications.

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