Protein-bound iodine (PBI)

Protein-bound iodine includes thyroxine (T4), triiodothyronine (T3), monoiodotyrosine, diiodotyrosine, and iodine contained in trace thyroglobulin. While most of the serum protein binding iodine is iodine in thyroxine, the determination of protein-bound iodine can reflect the level of thyroid hormone. Basic Information Specialist classification: examination classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Hypothyroidism, post-thyroidectomy, familial thyroxine-binding protein reduction, anterior pituitary insufficiency, chronic adrenal insufficiency, nephrotic syndrome, cirrhosis, malnutrition, drug-induced (prednisone, ACTH) , thiouracil, phenytoin, testosterone, salicylate, chlorpromazine, mercury diuretic). Normal value: PBI: 0.32 μmol/L - 0.63 μmol/L μmol/L or μg/dl PBI: 4μg/dl-8μg/dlμmol/L or μg/dl Above normal: Hyperthyroidism, acute thyroiditis, familial thyroxine-binding globulin, viral hepatitis, pregnancy, drug effects (iodine-containing drugs). negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. After 8 pm on the day before the medical examination, you should start fasting for 12 hours, normal value. 0.32 to 0.63 μmol/L (4 to 8 μg/dl). Clinical significance (1) increase hyperthyroidism, acute thyroiditis, familial thyroxine-binding globulin, viral hepatitis, pregnancy, drug effects (including iodine drugs). (2) reduce hypothyroidism, thyroidectomy, familial thyroxine binding protein reduction, anterior pituitary dysfunction, chronic adrenal insufficiency, nephrotic syndrome, cirrhosis, malnutrition, drug-induced (strong Pine, ACTH, thiouracil, phenytoin, testosterone, salicylate, chlorpromazine, mercury diuretic). Low results may be diseases: adrenal crisis, nephrotic syndrome, viral hepatitis, high results may be diseases: hypothyroidism, thyroid hyperthyroidism precautions First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. 3. Please inform the doctor about the recent medication and special physiological changes before the test. Inspection process Thyroid hormone determination. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

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