Extractable Nuclear Antigen (ENA)
The extractable nuclear antigens are mainly anti-ribonucleoprotein (RNP) antibodies and anti-Sm antibodies. Methods Six kinds of antibodies (anti-Sm antibody, anti-RNP antibody, anti-SSa antibody) were detected by immunoblotting (WB) method Wanfu reagent and purified antigen immunospot assay Trinity reagent and Euromonal reagent. Anti-SSb antibody, anti-Scl-70 antibody and anti-Jo-1 antibody. Basic Information Specialist classification: examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: abnormal. Tips: Do not wear clothes that are too small or too tight, so as to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Normal value Immunoblotting was negative. Convection immunoelectrophoresis was negative. Clinical significance Abnormal results anti-Sm antibody positive systemic lupus erythematosus. Anti-U1RNP antibody positive mixed connective tissue disease. Anti-SS-A antibody and anti-SS-B antibody positive Sjogren's syndrome. Anti-Scl-70 antibody positive scleroderma. Anti-Jo-1 antibody positive judgment of polymyositis and dermatomyositis have a certain value. Anti-Rib antibody positive systemic lupus erythematosus. Need to check the diagnosis of abnormal skin, muscle, joint abnormalities. Precautions Inappropriate people: generally no special population. Taboo before the examination: It is necessary to cooperate with the doctor to write the correct name, neat and tidy, to avoid confusion caused by the same name or similar names. With these in mind, blood draws are more convenient and faster, and you can better save yourself time for diagnosis. Requirements for inspection: Do not wear clothes that are too small or too tight in cuffs to avoid the sleeves being too tight when blood is drawn or the sleeves are too tight after blood drawing, causing blood vessels in the arms. Different laboratory items should be asked by the doctor and treated differently. Inspection process Methods Six kinds of antibodies (anti-Sm antibody, anti-RNP antibody, anti-SSa antibody) were detected by immunoblotting (WB) method Wanfu reagent and purified antigen immunospot assay Trinity reagent and Euromonal reagent. Anti-SSb antibody, anti-Scl-70 antibody and anti-Jo-1 antibody). Not suitable for the crowd There are no special taboos. Adverse reactions and risks There are no related complications and hazards.
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