Skeletal muscle autoantibodies (ASA)
A method of examination for myasthenia gravis. The positive rate of anti-skeletal acetylcholine receptor antibody in patients with myasthenia gravis is up to 95%. Other diseases that cause anti-skeletal muscle autoantibodies are polymyositis, dermatomyositis and idiopathic muscular atrophy. Basic Information Specialist classification: neurological examination classification: immune examination Applicable gender: whether men and women apply fasting: not fasting Tips: When chewing or swallowing, you should pay attention to soft food and semi-liquid food to avoid cough and lung infection. Normal value negative. Clinical significance The positive rate of anti-skeletal acetylcholine receptor antibody in patients with myasthenia gravis is up to 95%. Other diseases that cause anti-skeletal muscle autoantibodies are polymyositis, dermatomyositis and idiopathic muscular atrophy. Precautions To ensure the specificity and sensitivity of the test, whether it is granular antigen, tissue extract, peptide antigen, recombinant antigen must be purified, otherwise it will easily produce non-specific reactions. In the application of labeled immunoassay, it can cause an increase in the background value, which greatly affects the accuracy of the test. Inspection process Indirect fluorescent immunoassay. Not suitable for the crowd There are no taboos. Adverse reactions and risks There are no related complications and hazards.
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