Chlorpromazine test

The chlorpromazine test is an examination that aids in the identification of bronchial asthma and cardiogenic asthma. Basic Information Specialist Category: Respiratory Examination Category: Other Inspections Applicable gender: whether men and women apply fasting: not fasting Tips: Pay attention to normal eating habits and pay attention to personal hygiene. Normal value No Information Clinical significance Abnormal result Cardiac asthma has a history of hypertension or heart disease. In asthma, it is accompanied by frequent coughing, coughing, especially bloody sputum, heart enlargement, arrhythmia and heart sound abnormalities. Main clinical manifestations of bronchial asthma (1) Episodes of upper respiratory tract with expiratory dyspnea with wheezing, or paroxysmal chest tightness and cough. Severe cases are forced to take a seat or sit on the breath, dry cough or cough a lot of white foam, and even cyanosis. Cough is the only symptom of cough variant asthma. Asthma symptoms can last from hours to days, with bronchodilators or self-remission. (2) The lungs are characterized by an over-inflated state, a prolonged expiratory phase, and a wide and scattered wheezing sound. Severe asthma has increased heart rate, odd pulse, abnormal chest and abdomen movement and cyanosis. The population in need of examination failed to identify patients who were bronchial asthma or cardiogenic asthma. Precautions Forbidden before examination: Pay attention to normal eating habits and pay attention to personal hygiene. Requirements for examination: The patient has not used theophylline drugs within 24 hours, and can be diluted intravenously with 0.25 g of aminophylline to relieve asthma symptoms. Do not use adrenaline or morphine at this time. Inspection process Cardiac asthma is a wheezing symptom of acute left ventricular dysfunction, which is easily confused with bronchial asthma. The two main points of differentiation can be summarized as follows: 1 history: bronchial asthma has a history of asthma attack, personal or family allergy history; cardiogenic Asthma has a history of hypertensive heart disease, a history of coronary heart disease, a history of rheumatic heart disease, or a history of syphilitic heart disease. 2 age of onset: bronchial asthma is more common in adolescents; cardiogenic asthma is more common in middle-aged and elderly. 3 Incidence season: bronchial asthma is more common in spring and autumn; the seasonal onset of cardiogenic asthma is not obvious. 4 pulmonary signs: bronchial asthma is characterized by prolonged expiratory time, audible and extensive wheezing sound, if there is sputum, it is white foam sputum; cardiogenic asthma can be heard in the lungs and more dry voice There are a lot of pink foam 痰. 5 cardiac signs: bronchial asthma without heart disease is normal; patients with cardiogenic asthma can see left heart enlargement, galloping and pathological murmur. 6 chest X-ray examination: bronchial asthma lung field clear or increased brightness; cardiogenic asthma can be seen in pulmonary congestion and left heart enlargement. 7 effective treatment drugs: bronchial asthma with β2 receptor agonist, aminophylline; cardiogenic asthma requires digitalis, morphine, diuretics, aminophylline. The chlorpromazine test is helpful in the differential diagnosis of bronchial asthma and cardiogenic asthma by: after giving intramuscular injection of chlorpromazine 5 mg, the patient's wheezing, dyspnea symptoms and signs disappeared or significantly reduced within 5 to 15 minutes. It is positive for chlorpromazine test and supports the diagnosis of cardiogenic asthma. If the patient has no significant improvement in wheezing, dyspnea symptoms and signs, it is judged to be negative for chlorpromazine test, which may be considered as bronchial asthma. The reported chlorpromazine test was negative in 20 patients with various types of asthma. In addition, some patients had a slight increase in heart rate and a slight decrease in blood pressure, and no other adverse reactions were observed. Not suitable for the crowd Inappropriate crowd: No.

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