Pancreatic tumor marker (CA 19-9)

CA19-9 is a related antigen of pancreatic cancer. Its expression depends on the expression of lewis blood group antigen. The diagnosis of Lewis-negative CA19-9 is also negative. CA19-9 sensitivity and accuracy of diagnosis of pancreatic cancer are 83.1% 73%75, respectively. % of small pancreatic cancer patients with CA19-9 level is less than 2cm, the positive rate of adenocarcinoma is only 60.7%, and the level of CA19-9 is higher. The positive rate of CA19-9 is more than 80%. The cutoff value is set at 120kU/L. This value is highly suspected of pancreatic cancer and can also determine the prognosis. After the tumor is resected, the CA19-9 drops to the normal value. The serum cut-off value is 30kU/L. The prognosis is good. If the tumor recurs or metastasis or the disease deteriorates, the CA19-9 can be significantly increased again. Therefore, CA19-9 is an effective marker for pancreatic cancer. Basic Information Specialist classification: Oncology examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Detection of normal serum CA19-9 Positive: No relevant information. Tips: Take a blood sample on an empty stomach. Normal value The normal value of serum CA19-9 was <37 u/L. Clinical significance Abnormal results: Pancreatic tumors are one of the most common malignant tumors in the digestive tract. They are the most common malignant tumors and occur mostly in the head of the pancreas. Abdominal pain and painless jaundice are common symptoms of pancreatic head cancer. Diabetic patients have long-term large-volume smoking, high-fat high-protein protein diet, the incidence is relatively high, the disease is more common in middle-aged and elderly people, male patients are far more than premenopausal women, the incidence of postmenopausal women is similar to men. The cause of the disease is still unclear, and some environmental factors are found to be related to the occurrence of pancreatic cancer. The primary risk factors that have been determined are smoking, diabetes, cholelithiasis (including beer), and chronic pancreatitis, such as high-fat, high-protein diets and refined flour foods. Gastric resection is also a risk factor for pancreatic cancer, and its rate is extremely high. People who need to be examined: diabetic patients, patients with renal insufficiency, and patients with abnormal pancreatic function. Precautions Contraindications before examination: Blood samples should be taken on an empty stomach. Requirements for inspection: serum samples should be taken in time and attention should be paid to cryopreservation. Inspection process Determined by immunosolid phase method. Not suitable for the crowd Inappropriate crowd: None. Adverse reactions and risks No relevant information.

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