sleep test

The sleep test was carried out by the following principle. The secretion of human growth hormone (hGH) is regulated by a variety of neurological and humoral factors, and its peaks and valleys are also circadian rhythm. The secretion of hGH in normal people is more than that in the daytime, and more sleep than when awakening, especially 45-90 minutes after falling asleep, the secretion reaches a peak. Sympathetic nerves are excited during exercise, and elevated levels of adrenaline and norepinephrine in the blood also promote the secretion of hGH. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: No relevant information. Normal value: Normal male aged 1-20 years: 5.1±5.3-1.5±1.5μg/L Female: 10.3±10.6-5.0±6.4μg/L Above normal: No relevant information. negative: Positive: Tips: Pay attention to the normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Normal value Normal human blood hGH levels decrease with age. In China, normal males aged 1 to 20 years old (5.1±5.3) μg/L-(1.5±1.5) μg/L, and women (10.3±10.6) μg/L-(5.0±6.4) μg/L. Clinical significance This test can only be used as a screening test for growth hormone deficiency (GHD). Those with positive test results can only exclude GHD. Negative patients cannot diagnose GHD. Other tests are needed. Abnormal results: idiopathic growth hormone deficiency is more common in boys, male: female = 3:1, children with elevated and normal body weight at birth, growth rate slows after 1 year old, growth is more serious than low weight The increase is lower than the third percentile (or less than two standard deviations) of the growth curve of normal healthy children of the same age, and the growth rate of height is less than 4cm, and the intelligent development is normal. The child's head is round, his face is childish, his face is fat, his skin is delicate, his hair is slender, his jaw and ankle are stunted, his teeth are delayed and the arrangement is not neat. Although the child grows behind, the proportion of the body is evenly proportioned, which is consistent with his actual age. . Most puberty development is delayed. Some children with growth hormone deficiency are accompanied by one or more other pituitary hormones. In addition to growth retardation, these patients have other symptoms associated with adrenocorticotropic hormone (ACTH) deficiency and are prone to hypoglycemia. Thyroid hormone (TSH) deficiency may have symptoms of mild hypothyroidism such as loss of appetite and inactivity, accompanied by gonadal dysplasia in gonadotropin deficiency, and small penis (ie, straight penis length less than 2.5 cm). Until puberty, there are still no sexual organs and secondary sexual development. Organic growth hormone deficiency can occur at any age, with those caused by abnormal perinatal conditions, often accompanied by symptoms of diabetes. It is worth noting that intracranial tumors have symptoms such as increased headache, vomiting, visual field defects and other symptoms of intracranial pressure and optic nerve compression. People who need to be examined: patients with growth delay, short stature, and other patients with growth hormone deficiency. Precautions Forbidden before examination: pay attention to normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Requirements for inspection: Actively cooperate with the doctor's request. (1) The environment should be quiet during the test, and the light should not be too strong, so as not to affect the deep sleep. (B) This test only takes blood once, the accuracy is low, and the positive rate of normal children is only 69%. Inspection process method: Venous blood was taken 60 minutes after deep sleep, and the hGH concentration was measured. After deep sleep, the blood hGH>15μg/L, which is positive for the test, indicates that the GH function is abnormal. Not suitable for the crowd Inappropriate crowd: temporarily unknown. Adverse reactions and risks No obvious complications and harms.

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