Thrombocytopenia (PCT)

Platelet pressure (PCT), clinically measured platelet mean volume (MPV) and platelet distribution width (PDW), PCT = MPV * PLT, affected by platelet mean volume (MPV) and platelet distribution width (PDW). MPV indicates the average volume of a single platelet, which is reduced by 1. Bone marrow hematopoietic dysfunction, decreased platelet production, 2. MPV reduction in half of leukemia patients, 3. Mpv with platelet count continues to decline, is one of the signs of bone marrow hematopoietic failure. Pdw indicates the dispersion of platelet volume size, and low indicates that the platelet size is relatively uniform. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: There are many drugs that can cause elevated or decreased platelets, such as adrenaline, glucocorticoids, etc.; phenytoin, phenylbutazone, chlorpromazine, chloramphenicol, cyclophosphamide, digitoxin , codeine, tazobactam, diuretic acid, chlorpheniramine, streptomycin, doxycycline, etc. can reduce thrombocytopenia. Normal value The reference value is 0.10-0.35% for males, 0.10-0.35% for females, and 0.10-0.35% for newborns. Clinical significance The reason for the increase in platelet count (PCT) may be an increase in MPV, indicating that megakaryocytes are highly mature and bone marrow-derived platelets are good. PLT is elevated, that is, the total number of platelets is increased. The general test is within 450 units, which is acceptable. General infection, blood loss, hemolysis, and tumors all increase platelets. If it is too high (excluding other blood diseases), it is thrombocytosis, and it is necessary to find out the cause (primary or secondary). Vasoconstriction also causes an increase in PCT, which is because platelets adhere to the vascular endothelium. When the blood vessels are damaged and contracted, the glycoprotein on the surface of the platelets adheres to the collagen under the endothelium, and the aggregation between the platelets. To make the platelets pile up, the natural compaction will also increase. The reason for the decrease in platelet count (PCT) may be that MPV indicates the average volume of individual platelets, which is reduced by (1) bone marrow hematopoietic dysfunction and decreased platelet production; (2) half of patients with leukemia have decreased MPV; (3) mpv with platelet count Continued decline is one of the hallmarks of bone marrow hematopoietic failure. PDW indicates the dispersion of platelet volume size, and low indicates that the platelet size is relatively uniform. However, these indicators are generally analyzed by an automatic blood cell analyzer. There are instrument errors. It is more important to look at the number of platelets. If the number is normal, there is generally no problem. Low results may be diseases: children with primary thrombocytosis, leukemia, thrombocytopenic purpura high results may be diseases: thrombocytopenia precautions (1) The platelet count can differ by 6% to 10% at different times within one day, which is lower in the morning and slightly higher in the afternoon; lower in spring and slightly higher in winter. (2) The residents in the plain area are lower, the plateau area is higher; the exercise is higher, rest after rest; lower before menstruation, and rise after menstruation. (3) Venous blood is higher than finger blood. (4) Because there are many factors affecting the platelet count, it is difficult to obtain accurate results in one test, and it should be counted several times to determine whether there is any change. (5) There are many drugs that can cause elevated or decreased platelets, such as adrenaline, glucocorticoids, etc.; phenytoin, glutamine, phenylbutazone, chlorpromazine, chloramphenicol, cyclophosphamide , vincristine, digoxigenin, sulfonamides, spironolactone, codeine, tazobactam, diuretic acid, chlorpheniramine, streptomycin, doxycycline, etc. can reduce thrombocytopenia. Inspection process Subjects were venously collected, and serum was separated in time and then measured by an automatic blood cell analyzer. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

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