hemagglutination inhibition test
A virus with hemagglutinin (HA) can agglutinate human or animal red blood cells, which is called blood coagulation. The inhibition of blood coagulation by the corresponding antibody is called hemagglutination inhibition test, a technique for measuring antigen or antibody, that is, the addition of a specific antibody or a specific antigen, the original hemagglutination reaction is inhibited. It is commonly used for auxiliary diagnosis and epidemiological investigation of Orthomyxovirus, Paramyxovirus and Flavivirus. It can also be used to identify virus type and subtype, and different virus antibodies will be the same. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Negative is generally a normal phenomenon. Positive: Prompt for a viral infection. Tips: Taboo overeating and strenuous exercise, usually in the morning fasting test. Normal value The results after the test were negative. Clinical significance Abnormal result After the corresponding antibody binds to the virus, it prevents the surface HA from binding to the red blood cells, and is commonly used for auxiliary diagnosis and epidemiological investigation of Orthomyxovirus, Paramyxovirus and Flavivirus, and can also be used for identifying virus type and subtype. People who need to be examined: Newborns and pregnant women need, and patients with related viruses to make medical measurements. Positive results may be diseases: pediatric influenza virus pneumonia, mumps, Coxsackie virus rash, acquired pneumonia in the elderly, toxic purpura, myocarditis, mental disorders associated with JE, Echovirus rash, herpes pharynx Glare inflammation, pediatric influenza precautions Taboo before the test: taboo overeating, and strenuous exercise, usually in the morning fasting test. Requirements for inspection: Pay attention to the temperature inside the room during the test. Note that the serum samples are not contaminated, which may lead to false positive results. Inspection process The first is to obtain serum samples from the tester, to identify the blood test of the virus, and finally to determine the blood coagulation titer. The examination process is mainly the operation of the doctor. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.
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