Plasma tissue plasminogen activator antigen detection
Plasma tissue plasminogen activator antigen detection is the detection of plasma tissue plasminogen activator antigen in humans. For the diagnosis of the presence of active diseases of the fibrinolytic system. Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Negative is generally normal. Positive: Mainly seen in prethrombotic state and thrombotic disease. Tips: Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. Normal value The test result was negative, 1--12 μg/L. Clinical significance Abnormal result The test results were positive, indicating the presence of plasma tissue plasminogen activator antigen, mainly found in prethrombotic state and thrombotic diseases such as myocardial infarction, angina pectoris, cerebrovascular disease, diabetes, pregnancy-induced hypertension, deep vein thrombosis, nephropathy Syndrome, etc. The elderly population in the population to be examined, with limb pain, swelling, superficial venous engorgement and cords that can be touched along the vein. Positive results may be diseases: angina pectoris, pregnancy hypertension disease precautions Taboo before the test: Do not eat too greasy, high-protein foods the day before the test, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Requirements for examination: When taking blood, you should relax your mind to avoid the contraction of blood vessels caused by fear and increase the difficulty of blood collection. Inspection process In the ELISA method, the purified anti-t-PA monoclonal antibody is coated on the enzyme-labeled reaction plate, and the test plasma is added. The t-PA in the plasma is bound to the antibody coated on the reaction plate, and then the enzyme-labeled t is added. The -PA antibody, the enzyme-labeled antibody binds to t-PA bound to the reaction plate, and finally the substrate is added for color development, and the color depth is positively correlated with the content of t-PA in the test plasma. The plasma t-PA content was calculated from the standard curve. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.
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