free triiodothyronine index
The free bioactive part of thyroxine can directly reflect the thyroid function, and is not affected by the change of TBG, but the content is very small, the determination is difficult, and the required reagent price is also expensive. Clinically, the free thyroxine index (FT4I, FT3I) can be used to reflect serum free thyroxine levels indirectly. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: FT3I is reduced in cirrhosis, nephropathy, and the like, and low T3 syndrome. Normal value: FT4I: 5.45-12.8 FT3I: 46.75-21.55 Above normal: Hyperthyroidism increased. negative: Positive: Tips: Stop eating iodine-rich foods before checking. Normal value FT4I: 5.45~12.8 (8.09±1.6) FT3I: 46.75~21.55 (126.25±36.08) Clinical significance FT4I and FT3I can better reflect thyroid function, and the hyperthyroidism is increased, and the hypothyroidism is reduced. FT3I is reduced in cirrhosis, nephropathy, and the like, and low T3 syndrome. Low results may be diseases: high cirrhosis results may be diseases: endemic goiter considerations 1. Before the inspection, you must stop eating foods rich in iodine, such as kelp, seaweed, sea fish and shrimp, etc., depending on the amount of food, stop eating for 2 to 4 weeks. 2. The following drugs should be stopped before the examination. According to the dosage and time, stop taking 2~8 weeks. (1) Iodine-containing drugs, such as iodide, compound iodine solution, iodine-containing tablets, and the like. (2) Drugs that affect thyroid function, such as thyroid tablets, antithyroid drugs, etc. (3) Some Chinese herbal medicines, such as seaweed, kelp, fritillary, burdock, Mutong, etc. 3. The patient should be fasted on the day of the examination. 4, venous blood 2ml, not anticoagulation, separation of serum for determination. Inspection process Reagent (1) 125I-T3 (MAA): The bottle contains 1 magnet, stored at 4 ° C. (2) Standard human serum and high and low control serum: each bottle was dissolved with 0.5 ml of distilled water. Method of operation The operation process is shown in Table 1. Not suitable for the crowd Special diseases: Patients with hematopoietic dysfunction, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, dizziness or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 2. Risk of infection: If you use an unclean needle, you may be at risk of infection.
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