Serum Selenium (Se)

The total amount of selenium in adults is about 14-21 mg. After selenium absorbed from the intestine enters the plasma, it is mainly transported to the whole body tissue in combination with blood globulin and lipoprotein. It is mainly stored in liver, kidney, spleen, lung, heart muscle and blood. About one-third of selenium is present in glutathione peroxidase and has antioxidant activity. Its content is rarely excreted before it is unsaturated in the body. Excess selenium entering the body can be converted into volatile dimethyl selenium from the liver and excreted from exhalation. The main excretion pathway of selenium is still urine. The physiological function of selenium in the body is to maintain the normal metabolism of the heart muscle; as a natural antidote to natural antioxidants and heavy metals in the body; selenium is also related to immunity, maintaining the physiological functions of heart, brain, liver, muscle and immunity. Chronic selenium deficiency in humans is also closely related to the occurrence of diseases such as cancer, cardiovascular disease, and endemic cardiomyopathy (Keshan disease). Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Fasting should be done after 8 pm on the day before the medical examination, so as not to affect the test of the next day. Normal value Spectrophotometry (AAS): 1.27 to 2.4 μmol/L (10 to 18.9 μg/dl0). Clinical significance 1. Increased in local selenium poisoning and acute selenium poisoning. The latter can cause chemical pneumonia due to a large amount of inorganic selenide inhalation; it causes severe chemical gastroenteritis when taken orally; all of them see serum selenium and urine selenium increase. 2, reduced in Keshan disease, Kashin-Beck disease, coronary heart disease, high blood pressure, heart disease, heart and kidney heart disease, breast cancer. Low results may be diseases: Keshan disease, Kashin-Beck disease, high coronary heart disease may be a disease: precautions for skin diseases caused by selenium and its compounds First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Take an appropriate amount of blood and immediately send it for inspection. Detection method: (1) methyl thymol blue colorimetric method (MTB). (2) o-cresol oxime complex ketone direct colorimetry. (3) Ethylenediaminetetraacetic acid disodium titration method. (4) Determination of ionic selenium. (5) Principle of the same atomic absorption spectrophotometry. Not suitable for the crowd Inappropriate people: Generally there are no people who are not suitable. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.

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