plasma vitamin B12

Plasma vitamin B12 is a water-soluble vitamin, and folic acid is collectively called red blood cell maturation factor, which is involved in DNA synthesis of various tissue cells. Plasma vitamin B12 is mainly used for the etiological diagnosis of megaloblastic anemia. A decrease of less than 58.2 pmol/L (100 pg/ml) is a vitamin B12 deficiency, and between 58.2 and 74.0 pmol/L (100 to 200 pg/ml), DNA synthesis abnormalities or neurological disorders may occur. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: A decrease of less than 58.2 pmol/L (100 pg/ml) is a vitamin B12 deficiency, and between 58.2 and 74.0 pmol/L (100 to 200 pg/ml), DNA synthesis abnormalities or neurological disorders may occur. Reduced vitamin B12 can be seen in the following conditions: (1) long-term vegetarians, long-term alcoholics; (2) megaloblastic anemia; (3) postoperative gastrectomy; (4) intestinal malabsorption; (5) intestinal parasitic Insect diseases; (6) malignant tumors; (7) long-term use of drugs that inhibit DNA synthesis (such as anti-tumor drugs and partial immunosuppressants) or antacids and other drugs. Normal value: Plasma vitamin B12: 74-516pmol/L Above normal: Elevation can be seen in the following conditions: (1) leukemia, acute and chronic myelogenous leukemia, lymphocytic leukemia, monocytic leukemia; (2) leukocytosis; (3) polycythemia vera; (4) Some patients with malignant tumors; (5) patients with liver diseases. negative: Positive: Tips: It is not advisable to eat animal liver, fermented bean curd and other foods rich in vitamin B12 before testing. Normal value Plasma: 74 to 516 pmol/L. Serum: 103-516 pmol/L for adults; 81-590 pmo/L for <60 years old. Clinical significance 1, lower Below 58.2 pmol/L (100 pg/ml), vitamin B12 deficiency may occur, and between 58.2 and 74.0 pmol/L (100 to 200 pg/ml), DNA synthesis abnormalities or neurological disorders may occur. Vitamin B12 is reduced, which can be seen in the following cases: (1) long-term vegetarians, long-term alcoholics; (2) megaloblastic anemia; (3) after gastrectomy; (4) poor intestinal absorption; (5) intestinal parasitic diseases; (6) malignant tumors; (7) Long-term use of drugs that inhibit DNA synthesis (such as anti-tumor drugs and partial immunosuppressants) or antacids. 2, elevated, can be seen in the following situations: (1) acute and chronic leukemia, lymphocytic leukemia, and monocytic leukemia; (2) leukocytosis; (3) polycythemia vera; (4) Some patients with malignant tumors; (5) Patients with liver disease. Low results may be diseases: eosinophilia, megaloblastic anemia, high nutritional anemia results may be diseases: iron deficiency dysphagia precautions 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2, before the test should not eat animal liver, fermented bean curd and other foods rich in vitamin B12. 3, it is best to fast after 8 o'clock in the evening before the physical examination, take fasting blood for testing. Inspection process Blood is collected by venous blood, and an appropriate amount of blood is taken and sent to the laboratory for microbiological assay. Not suitable for the crowd Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the test, and patients with a history of drug administration in the near future are prohibited. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.

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