Anti-nucleosidase test

The nucleosidase is one of the extracellular enzymes produced by group A type B hemolytic streptococcus. The nucleosidase is antigenic like several other enzymes, and the body can produce anti-nucleosidase (denine) anti- nucleosidase (ANAD) antibodies. Basic Information Specialist classification: Respiratory examination classification: pathogenic microbiological examination Applicable gender: whether men and women apply fasting: fasting Tips: Hypercholesterolemia, multiple myeloma and macroglobulinemia can cause false positives. Normal value Normal value: < 1: 275. Clinical significance ANAD is one of the evidences for group A hemolytic streptococcal infection. In patients with acute rheumatic fever, the ANAD titer can be significantly increased. Elevation of ANAD can also be seen in other group A hemolytic streptococcal infection-associated diseases. Positive results may be diseases: rheumatic fever, macroglobulinemia, multiple myeloma considerations Patients with hypercholesterolemia, multiple myeloma, and macroglobulinemia may have false positives; false positives may occur when patients are treated with large amounts of antibiotics or hormones in the early stages of onset. Inspection process 1. Principle of anti-nucleosidase assay: EIA is a special reaction that combines the specificity of antigen-antibody reaction with the efficient melting of enzymes. 2. Reagents: serum. 3. Method of operation: Use the EIA method of operation. Not suitable for the crowd Those who do not have an indication for examination should not do this check. Adverse reactions and risks Generally no complications and harm.

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