Urinary glutamyl transpeptidase (UGGT)

γ-GT is the most abundant γ-GT in the kidneys of various organs in the human body. In normal urine, γ-GT is derived from the kidney. Due to its large molecular weight, it only leaks into the urine when it is glomerular. During anesthesia, renal ischemia and drug damage to the kidney, interstitial nephritis active period, acute tubular necrosis, epidemic hemorrhagic fever, chronic pyelonephritis active urinary γ-GT increased. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: No clinical significance. Normal value: Urine glutamyl transpeptidase: 21.56-31.7 mg / L Above normal: During anesthesia, renal ischemia and drug damage to the kidney, interstitial nephritis active period, acute tubular necrosis, epidemic hemorrhagic fever, chronic pyelonephritis active urinary γ-GT increased. negative: Positive: Tips: Normal urinary γ-GT is derived from the kidney. Because of its large molecular weight, it only leaks into the urine when it is glomerular. Normal value The reference value is 21.56 to 31.7 mg/L. (Note the specific reference value depends on each laboratory.) Clinical significance 1. When the upper urinary tract infection occurs, the urinary γGT is elevated; while the lower urinary tract infection is normal. 2, anesthesia, cardiac surgery, renal ischemia and drug damage to the kidney, interstitial nephritis active period, acute tubular necrosis, epidemic hemorrhagic fever, chronic pyelonephritis active urinary γ-GT increased. 3. When the renal reaction is rejection, the urinary γ-GT is elevated. High results may be diseases: acute tubular necrosis, interstitial nephritis, chronic pyelonephritis, urinary tract infections Use the patient's mid-stage urine test. Inspection process Serum creatinine can account for about 20% of total hair color strength (about 50% in red blood cells) when serum is used as a sample. In addition, some cephalosporins such as methoxythiophene cephalosporin can also react with picric acid to develop color and cause positive interference. The kinetic method developed according to the Jaffé reaction principle is based on the difference in reaction rate between creatinine and the above non-creatinine chromogen, that is, the latter reacts with picric acid more slowly than the former, and uses this to avoid interference from non-specific reactions. . Not suitable for the crowd Menstrual women. Adverse reactions and risks no.

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