Pediatric Hand-Heart Deformity Syndrome

Hand-heart malformation syndrome is cardiovascular-limb syndrome, also known as Holt-Oram syndrome, atrial-finger syndrome, atrio-digital syndrome, cardiovascular syndrome of the upper extremities, Upper limb defects, atrial dysplasia, atrio-digital dysplasia syndrome, etc. The disease is an autosomal dominant hereditary disease, with cardiovascular malformations and skeletal malformations as the main clinical manifestations. It is a rare autosomal dominant inherited disease with congenital cardiovascular malformations and skeletal deformities in the upper limbs. In the late 1950s, two pediatricians working in the United States and Britain described the relationship between congenital hand abnormalities and congenital heart disease. Heart abnormalities vary widely, but hand abnormalities are radial dysplasia.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.