Intracranial chordoma

Chordoma is a destructive tumor that is rare in the skull, deep in the base of the skull. The clinical diagnosis is mainly based on two aspects: neurological symptoms and changes in typical imaging. Chordoma was first documented by Virchow in 1857, and Muller pointed out that chordoma was related to embryonic chordal residual tissue in 1858. Intracranial chordomas usually originate from the midline of the slope, are located outside the epidural, and grow slowly. It can grow forward to or next to the saddle, even into the skull, or down into the nasal cavity, or the back of the pharynx. It can also grow to the posterior cranial fossa, involve the cerebellar angle of one side bridge, or develop backward along the midline to compress the brain stem. Chordomas are located in the occipital region of the sphenoid, accounting for 35%, the spine accounting for 15%, and the palatine tail accounting for up to 50%.

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