Α1-antitrypsin-deficient panniculitis

α1-anti trypsin deficiency associated with paniculitis (α1-anti trypsin deficiency associated with paniculitis) was reported in 1972 as a subtype of nodular panniculitis. α1-Antitrypsin is a polypeptide glycoprotein synthesized by liver cells and is an inhibitor of serum protease. Its effect can affect trypsin, trypsin, urokinase, skin collagenase, neutral protease of multinucleated cells, and coagulation Cofactors, etc. The functions of these enzymes can regulate metabolism and inhibit inflammatory responses.

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