Acanthamoeba keratitis

Acanthamoeba is a small free-living protozoa that is widely distributed in nature. Acanthamoeba can cause human primary encephalitis and keratitis. Hundreds of cases have been reported worldwide since Acanthamoeba keratitis was first reported by Nagington et al. In 1974. Acanthamoeba keratitis is a serious blinding eye disease. Its main clinical features are severe eye pain, ring keratitis, and corneal radial neuritis. Mild damage to the cornea and reduced local resistance such as inappropriate use of corticosteroids make Acanthamoeba pathogens easily invade the cornea and cause disease.

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