Congenital testicular hypoplasia in children

Congenital testicular hypoplasia, also known as Klinefetter syndrome, is a sexual chromosome disease with a high incidence. Before chromosome identification, Klinefelter first reported the disease in 1942. Bradbury et al. 1 It was female X chromatin. In 1959, Jacobs and Strong first discovered that the chromosome karyotype of patients with the disease was 47, XXY. In older women, there are many opportunities for pregnancy. Testicular hypoplasia, infertility, and poor intelligence are caused by abnormal sex chromosomes. The symptoms of this disease are not obvious before puberty, so it is not easy to detect early.

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