Autoimmune disease

Autoimmune diseases refer to diseases caused by the body's own tissues caused by the immune response to autoantigens. Many diseases have been listed as autoimmune diseases one after another. It is worth mentioning that the existence of autoantibodies and autoimmune diseases are not two equivalent concepts. Autoantibodies can exist in normal people without autoimmune diseases, especially the elderly. Such as anti-thyroglobulin, thyroid epithelial cells, gastric parietal cells, nuclear DNA antibodies and so on. Sometimes, damaged or changed antigenicity can stimulate the production of autoantibodies. For example, when myocardial ischemia occurs, necrotic myocardium can lead to the formation of anti-cardiac autoantibodies, but this antibody has no pathogenic effect and is a secondary immune response. ?

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