Tricyclic antidepressant poisoning

Tricyclic antidepressant poisoning refers to poisoning caused by excessive or misuse of tricyclic antidepressants. Tricyclic antidepressants include amitriptyline, imipramine, doxepine, carbamazepine, clozapine, etc., mainly used to combat depression , Melancholy, negative, and de-inhibition. Antidepressants are mainly used in the mesencephalic (especially the hypothalamus) and limbic systems, and play an adjusting role in this part called the emotional center. Tricyclic antidepressants can prevent the recovery of biogenic amines and produce antidepressant effects. Acute poisoning occurs when a large amount of a drug is swallowed in an attempt to commit suicide. The dose of 1.5-3.0g can cause severe poisoning and death.

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