Caffeine and aminophylline poisoning

Caffeine and amino-phylline are both derivatives of xanthine, and their pharmacological effects are similar, with only differences in the strength of the effects. Sodium benzoate (caffeine) is a mixture of caffeine and sodium benzoate, containing 47% to 50% of anhydrous caffeine; aminophylline is a complex of theophylline and ethylenediamine. Caffeine poisoning is mostly caused by mistaken administration or excessive treatment dosage, and a small number is caused by intake of beverages containing a large amount of caffeine; occasionally infants and young children are highly sensitive to caffeine, and acute poisoning symptoms can occur due to trace amounts. The effective therapeutic amount of aminophylline is not much different from the amount of poisoning, among which poisoning can be caused by excessive oral administration, rectal medication, intramuscular injection and other medications, too short intervals between medications, large intravenous doses or rapid rates, etc. Due to the high sensitivity to this drug.

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