Pigmented urticaria

Urtica pigmentosa is a mast cell disease with round or oval pigmented spots or pigmented nodules. It becomes red and swollen after scratching and rubbing. It usually starts in childhood. In 1969, the Nettie ship first described the skin manifestations of the disease, called chronic urticaria with brown spots. Unna pointed out the relationship between the disease and mast cells. Ellis was the first to report that the disease was not only skin but also other organs such as liver , Spleen, bone marrow, and lymph nodes can all have infiltration of mast cells. Usually a benign process, the rash can resolve on its own in children.

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