Excessive growth hormone secretion

Gigantism and acromegaly are caused by excessive growth hormone secretion from the anterior pituitary gland. If the disease occurs after puberty and the epiphysis is fused, it appears as acromegaly; if the disease begins before puberty, the epiphysis is not yet fused , Manifested as giant disease; if the onset in adolescence, continues to develop after adulthood, it is manifested as acromegaly giant disease.

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