Spider finger

Marfan's Syndrome, also known as spider finger (toe) syndrome and slender finger syndrome, is a congenital hereditary connective tissue disease, an autosomal dominant inheritance, and has a family history. In 1896, French pediatrician B.-J.-A. Malfang first reported the disease, hence the name. The lesions mainly involve the bones, heart, muscles, ligaments, and connective tissue of the mesoderm. Skeletal deformities are most common, with slender tubular bones throughout the body, and slender fingers and toes that look like spider feet. The heart may have mitral regurgitation or prolapse, and aortic regurgitation. There may be subluxation of the lens, retinal detachment, and so on. Cardiovascular aspects are manifested as aortic dysplasia of the elastic fibers in the middle layer, and the aorta or common abdominal aorta dilates to form aortic aneurysms or common abdominal aortic aneurysms. After the aorta expands to a certain extent, it will cause aortic rupture and death. The incidence is about 0.04 ‰ to 0.1 ‰. Can be found in various races.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.