Pale, hair group, and flushing reactions in successive extremities

Raynaud's phenomenon (RP) is also called Raynaud's syndrome. It is characterized by three-phase reactions of pale, hair group and flushing at the extremities, which mostly occur in the upper limbs, are symmetrical on both sides, can also involve the lower limbs, or affect both the upper and lower limbs, and occasionally occur in the ears, nose, cheeks or collars. Often caused by cold or emotional agitation. During the onset, the fingers first become cold, the skin is pale, stiff, and even the fingers are difficult to move. At the same time, they feel numbness and acupuncture, and then the color becomes darker, dark red or blue-violet. In severe cases, some nails are also grouped. Then the skin color Lighter, diffuse flushing, increased beating sensation, and finally returned to normal. The recurrent Raynaud phenomenon can cause local ulcers, atrophy, hardening and even gangrene. But more common are the nutritional changes of the fingers (toes), often the tips of the fingers become sharp or lemon-shaped, and the nails can also be distorted. Raynaud's phenomenon can be divided into two types: primary and secondary. The cause of the former is unknown. It is a benign acral arteriospasm, also known as Raynaud's disease, which is more common in women. The latter is secondary to other diseases, that is, the manifestation of Raynaud's phenomenon in other diseases. Recent studies have shown that Raynaud's phenomenon not only affects the extremities, but can also occur in the internal organs of patients with connective tissue disease, mainly involving the lungs, heart, brain, and kidneys. As to whether Raynaud's phenomenon can cause damage to internal organs, various reports have been made .

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