Cardiac relaxation

Cardiac relaxation is mainly characterized by a lack of peristalsis in the esophagus, high pressure in the lower esophageal sphincter (LES), and a weakened relaxation response to swallowing movements. Clinical manifestations are dysphagia, food reflux, and discomfort or pain behind the lower sternum. This disease is a rare disease (estimated to be about 1 in every 100,000 people) and can occur at any age, but it is most common in the age group of 20 to 39 years. It is rare in children and is roughly equal in men and women, and is more common in Europe and North America. There is a potential risk of esophageal cancer if the disease is left untreated.

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