Phytohemagglutinin intradermal test
Skin test is the most commonly used in vivo test method to determine the body's cellular immune function. It is essentially a late-onset allergy (type IV). When the body is infected by some bacteria (such as Mycobacterium tuberculosis, Brucella), virus, or fungi, or it is exposed to some small molecules or haptens, when it is contacted with tissue proteins in the body to become a complete antigen The body will produce specifically sensitized lymphocytes against these antigenic substances. When the corresponding antigen enters the body again, local sensitized lymphocytes will release a variety of lymphokines. After 24 to 72 hours, it will lead to inflammation mainly dominated by monocyte infiltration, manifested as reddened and swollen skin. allergy. This response can be used as one of the indicators to judge the body's cellular immune function.
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