Serum interleukin 8

IL-8 is a low molecular weight (6-8kD) polypeptide. Monocytes, lymphocytes, fibroblasts, endothelial cells and other cells can produce this cytokine after being stimulated by LPS, TNF or IL-1. . The characteristic biological effect of IL-8 is chemotaxis and activation of neutrophils, and thus participate in neutrophil-mediated tissue damage. In many chronic inflammatory diseases, such as rheumatoid arthritis, psoriasis, etc., the abnormality of local or serum IL-8 production is abnormal. Quantitative detection of IL-8 is of great significance for studying the occurrence, development and guiding treatment of these diseases.

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